HitPredict

Interactor 1: ARF6 (P62330)
ADP-ribosylation factor 6 (EC 3.6.5.2)
Gene: ARF6

Interactor 2: SMAP1 (Q8IYB5)
Stromal membrane-associated protein 1
Gene: SMAP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	15659652
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Arf~ArfGap
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 175 Hs			1 467
+	Hs
		897381 ARF3_HUMAN (2-175): 4.91e-65: 198: 69.54		SMAP1_HUMAN (1-467): 8.37e-104: 319: 100.00
+	Hs
		574718 ARF4_HUMAN (1-173): 1.32e-70: 212: 64.74		SMAP2_HUMAN (7-467): 6.83e-87: 274: 42.43
+	Hs
		912911 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		ACAP2_HUMAN (3-361): 1.8e-79: 264: 18.84
+	Hs
		912909 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		ACAP1_HUMAN (2-360): 2.8e-69: 236: 19.15
+	Hs
		950577 ARF1_HUMAN (2-175): 4.43e-69: 209: 68.39		ASAP1_HUMAN (1-454): 1.6e-63: 224: 15.30
+	Mm
		1186345 RAB1B_MOUSE (10-174): 3.3e-66: 202: 19.41		ASAP2_MOUSE (4-465): 3.85e-65: 228: 16.74
+	Hs
		574712 ARF4_HUMAN (1-173): 1.32e-70: 212: 64.74		ARFG2_HUMAN (9-380): 4.13e-63: 214: 18.11
+	Hs
		913181 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		ASAP1_HUMAN (1-454): 1.6e-63: 224: 15.30
+	Hs
		950522 ARF1_HUMAN (2-175): 4.43e-69: 209: 68.39		ARFG2_HUMAN (9-380): 4.13e-63: 214: 18.11
+	Hs
		950654 ARF5_HUMAN (2-173): 4.69e-69: 209: 65.12		ARFG2_HUMAN (9-380): 4.13e-63: 214: 18.11
+	Hs
		574756 ARF4_HUMAN (1-173): 1.32e-70: 212: 64.74		ARFG3_HUMAN (9-355): 5.96e-59: 203: 18.34
+	Hs
		897383 ARF3_HUMAN (2-175): 4.91e-65: 198: 69.54		ARFG2_HUMAN (9-380): 4.13e-63: 214: 18.11
+	Hs
		950563 ARF1_HUMAN (2-175): 4.43e-69: 209: 68.39		ARFG3_HUMAN (9-355): 5.96e-59: 203: 18.34
+	Hs
		950718 ARF5_HUMAN (2-173): 4.69e-69: 209: 65.12		ARFG3_HUMAN (9-355): 5.96e-59: 203: 18.34
+	Hs
		950523 ARF1_HUMAN (2-175): 4.43e-69: 209: 68.39		ARFG1_HUMAN (13-342): 8.16e-57: 195: 16.29
+	Hs
		950579 ARF1_HUMAN (2-175): 4.43e-69: 209: 68.39		AGAP1_HUMAN (2-138): 2.52e-52: 191: 33.81
+	Hs
		273515 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		ADAP1_HUMAN (16-204): 1.52e-58: 198: 29.17
+	At
		285978 ARF2B_ARATH (2-173): 7.78e-65: 198: 70.93		AGD7_ARATH (18-411): 2.54e-55: 192: 14.87
+	Hs
		913191 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		AGAP1_HUMAN (2-138): 2.52e-52: 191: 33.81
+	Hs
		913052 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		AGAP3_HUMAN (3-150): 3.56e-47: 176: 36.42