HitPredict

Interactor 1: PRS10 (P62333)
26S proteasome regulatory subunit 10B (26S proteasome AAA-ATPase subunit RPT4) (Proteasome 26S subunit ATPase 6) (Proteasome subunit p42)
Gene: PSMC6

Interactor 2: DDI1 (Q8WTU0)
Protein DDI1 homolog 1 (EC 3.4.23.-)
Gene: DDI1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	27114451
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AAA~ubiquitin
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 389 Hs			1 396
+	Hs
		906885 PRS4_HUMAN (14-380): 2.44e-135: 395: 41.42		DDI1_HUMAN (1-396): 4.1e-163: 465: 100.00
+	Hs
		913291 PRS10_HUMAN (1-389): 7.27e-137: 397: 100.00		DDI2_HUMAN (1-392): 2.76e-155: 445: 70.93
+	Hs
		906853 PRS4_HUMAN (14-380): 2.44e-135: 395: 41.42		DDI2_HUMAN (1-392): 2.76e-155: 445: 70.93
+	Hs
		907106 PRS8_HUMAN (5-387): 7.73e-122: 360: 47.00		DDI1_HUMAN (1-396): 4.1e-163: 465: 100.00
+	Hs
		907059 PRS8_HUMAN (5-387): 7.73e-122: 360: 47.00		DDI2_HUMAN (1-392): 2.76e-155: 445: 70.93
+	Dm
		186166 PRS8_DROME (5-387): 4.86e-126: 370: 47.00		Q9VXF9_DROME (5-395): 3.91e-131: 386: 47.58
+	Hs
		913367 PRS10_HUMAN (1-389): 7.27e-137: 397: 100.00		UBQL1_HUMAN (5-249): 3.83e-47: 171: 14.74
+	Hs
		906946 PRS4_HUMAN (14-380): 2.44e-135: 395: 41.42		UBQL1_HUMAN (5-249): 3.83e-47: 171: 14.74
+	Hs
		913364 PRS10_HUMAN (1-389): 7.27e-137: 397: 100.00		UBQL2_HUMAN (5-249): 4.55e-46: 168: 14.74
+	Hs
		906941 PRS4_HUMAN (14-380): 2.44e-135: 395: 41.42		UBQL2_HUMAN (5-249): 4.55e-46: 168: 14.74
+	Hs
		913358 PRS10_HUMAN (1-389): 7.27e-137: 397: 100.00		UBQL4_HUMAN (8-249): 3.58e-43: 160: 14.24
+	Hs
		906929 PRS4_HUMAN (14-380): 2.44e-135: 395: 41.42		UBQL4_HUMAN (8-249): 3.58e-43: 160: 14.24
+	Dm
		1375073 Q9W414_DROME (5-389): 1.73e-131: 384: 89.35		Q9VWD9_DROME (5-249): 3.39e-41: 154: 13.55
+	Hs
		907185 PRS8_HUMAN (5-387): 7.73e-122: 360: 47.00		UBQL1_HUMAN (5-249): 3.83e-47: 171: 14.74
+	Hs
		907182 PRS8_HUMAN (5-387): 7.73e-122: 360: 47.00		UBQL2_HUMAN (5-249): 4.55e-46: 168: 14.74
+	Dm
		186163 PRS8_DROME (5-387): 4.86e-126: 370: 47.00		Q9VWD9_DROME (5-249): 3.39e-41: 154: 13.55
+	Hs
		907171 PRS8_HUMAN (5-387): 7.73e-122: 360: 47.00		UBQL4_HUMAN (8-249): 3.58e-43: 160: 14.24
+	Hs
		913239 PRS10_HUMAN (1-389): 7.27e-137: 397: 100.00		RS27A_HUMAN (5-93): 5.56e-24: 98.8: 17.98
+	Xl
		804064 PRS8_XENLA (5-387): 8.3e-124: 367: 46.74		BAG6A_XENLA (4-247): 1.18e-28: 120: 14.92
+	Hs
		906982 PRS8_HUMAN (5-387): 7.73e-122: 360: 47.00		RS27A_HUMAN (5-93): 5.56e-24: 98.8: 17.98