HitPredict

Interactor 1: RB11A (P62491)
Ras-related protein Rab-11A (Rab-11) (EC 3.6.5.2) (YL8)
Gene: RAB11A

Interactor 2: RFIP4 (Q86YS3)
Rab11 family-interacting protein 4 (FIP4-Rab11) (Rab11-FIP4) (Arfophilin-2)
Gene: RAB11FIP4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.856

Property	Details
Experiments	12470645, 16148947, 17030804
Identification Methods	far western blotting, two hybrid, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RBD-FIP~Ras
Common GO terms	GO:0005813 - centrosome GO:0032154 - cleavage furrow GO:0032465 - regulation of cytokinesis GO:0055038 - recycling endosome membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 216 Hs			1 637
+	Hs
		1079939 RB11B_HUMAN (1-216): 2.54e-91: 268: 90.37		RFIP4_HUMAN (1-637): 1.15e-56: 204: 100.00
+	Dm
		185688 O18335_DROME (1-214): 1.21e-88: 261: 85.51		Q8SYQ0_DROME (285-636): 2.03e-40: 156: 28.10
+	Dm
		185677 O18335_DROME (1-214): 1.21e-88: 261: 85.51		Q6NN29_DROME (335-636): 1.43e-39: 154: 26.95
+	Hs
		256700 RB11A_HUMAN (1-216): 2.38e-94: 276: 100.00		RFIP3_HUMAN (20-636): 5.64e-30: 128: 23.67
+	Hs
		256706 RB11B_HUMAN (1-216): 2.54e-91: 268: 90.37		RFIP3_HUMAN (20-636): 5.64e-30: 128: 23.67
+	Hs
		914042 RB11A_HUMAN (1-216): 2.38e-94: 276: 100.00		LIPA1_HUMAN (237-624): 1.2e-25: 115: 16.83
+	Hs
		256698 RAB25_HUMAN (2-190): 8.31e-87: 256: 67.20		RFIP3_HUMAN (20-636): 5.64e-30: 128: 23.67
+	Hs
		254466 RB11A_HUMAN (1-216): 2.38e-94: 276: 100.00		ROCK2_HUMAN (235-625): 8.05e-13: 73.8: 13.04