HitPredict

Interactor 1: E7EQG2 (E7EQG2)
Eukaryotic initiation factor 4A-II (EC 3.6.4.13) (ATP-dependent RNA helicase eIF4A-2)
Gene: EIF4A2

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32812023
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 362 Hs			1 758
+	Hs
		497009 IF4A2_HUMAN (1-359): 3.05e-133: 388: 100.00		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496251 DDX5_HUMAN (10-360): 2.73e-130: 387: 31.48		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497386 DDX17_HUMAN (11-360): 2.62e-127: 383: 31.48		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496685 IF4A1_HUMAN (3-359): 1.4e-129: 378: 89.92		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		133854 DDX3X_HUMAN (2-360): 2.56e-123: 371: 29.40		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Mm
		498056 DDX3Y_MOUSE (2-360): 1.08e-141: 418: 29.66		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Mm
		496125 IF4A2_MOUSE (1-359): 3.05e-133: 388: 100.00		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Mm
		498084 Q8BTS0_MOUSE (10-360): 3.38e-130: 387: 31.48		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Mm
		498030 DDX17_MOUSE (11-360): 2.98e-128: 383: 31.48		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Hs
		757612 IF4A3_HUMAN (5-360): 4.15e-123: 362: 67.14		MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57
+	Dm
		1367483 IF4A3_DROME (10-360): 4.99e-123: 361: 68.95		Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96