HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: CEP89 (Q96ST8)
Centrosomal protein of 89 kDa (Cep89) (Centrosomal protein 123) (Cep123) (Coiled-coil domain-containing protein 123)
Gene: CEP89

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 783
+	Hs
		925544 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		CEP89_HUMAN (1-783): 8.03e-53: 198: 100.00
+	Hs
		900829 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		CEP89_HUMAN (1-783): 8.03e-53: 198: 100.00
+	Hs
		925344 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		MRCKA_HUMAN (197-717): 8.92e-48: 186: 17.03
+	Hs
		900570 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		MRCKA_HUMAN (197-717): 8.92e-48: 186: 17.03
+	Hs
		915741 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		MRCKA_HUMAN (197-717): 8.92e-48: 186: 17.03
+	Hs
		545430 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		MRCKA_HUMAN (197-717): 8.92e-48: 186: 17.03
+	Hs
		724757 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		MYH9_HUMAN (268-774): 1.96e-23: 109: 12.33
+	Hs
		925766 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		MRCKB_HUMAN (408-744): 1.12e-17: 90.5: 15.30
+	Hs
		925488 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		MY18A_HUMAN (39-550): 9.2e-17: 87.5: 10.73
+	Hs
		901094 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		MRCKB_HUMAN (408-744): 1.12e-17: 90.5: 15.30
+	Hs
		916101 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		MRCKB_HUMAN (408-744): 1.12e-17: 90.5: 15.30
+	Hs
		900754 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		MY18A_HUMAN (39-550): 9.2e-17: 87.5: 10.73
+	Hs
		915875 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		MY18A_HUMAN (39-550): 9.2e-17: 87.5: 10.73
+	Hs
		925356 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		MRCKG_HUMAN (200-548): 3.09e-15: 82.4: 14.91
+	Hs
		148653 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		CTRO_HUMAN (73-685): 3.76e-13: 75.8: 12.74
+	Mm
		823530 RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10		CTRO_MOUSE (97-671): 3.87e-12: 72.4: 11.70
+	Hs
		148608 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		CTRO_HUMAN (73-685): 3.76e-13: 75.8: 12.74
+	Hs
		148632 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		CTRO_HUMAN (73-685): 3.76e-13: 75.8: 12.74
+	Rn
		92842 RHOA_RAT (1-196): 3.27e-78: 233: 83.16		CTRO_RAT (68-671): 2.21e-12: 73.1: 11.92
+	Mm
		823539 RHOA_MOUSE (1-196): 3.27e-78: 233: 83.16		CTRO_MOUSE (97-671): 3.87e-12: 72.4: 11.70