HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: RFIP5 (Q9BXF6)
Rab11 family-interacting protein 5 (Rab11-FIP5) (Gamma-SNAP-associated factor 1) (Gaf-1) (Phosphoprotein pp75) (Rab11-interacting protein Rip11)
Gene: RAB11FIP5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RBD-FIP~Ras
Common GO terms	GO:0005769 - early endosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 653
+	Hs
		925583 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Hs
		545594 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Hs
		951290 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		RFIP5_HUMAN (1-653): 4.01e-162: 482: 100.00
+	Ce
		136793 RAC1_CAEEL (1-196): 5.29e-80: 238: 53.57		UNC89_CAEEL (164-653): 4.53e-35: 145: 9.40
+	Hs
		297823 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Ce
		104464 G5EBV3_CAEEL (2-196): 7.03e-76: 227: 48.72		UNC89_CAEEL (164-653): 4.53e-35: 145: 9.40
+	Hs
		297820 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Hs
		297822 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Ce
		136800 RHO1_CAEEL (1-196): 4.36e-75: 225: 78.57		UNC89_CAEEL (164-653): 4.53e-35: 145: 9.40
+	Hs
		297812 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Hs
		297809 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Hs
		297827 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Hs
		915784 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		RFIP2_HUMAN (459-653): 4.72e-26: 114: 21.72
+	Hs
		925372 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		900608 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		915772 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		545456 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		436367 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		951094 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14
+	Hs
		894148 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		RFIP1_HUMAN (405-650): 1.82e-10: 66.4: 21.14