Protein: P121A
Nuclear envelope pore membrane protein POM 121 (Nuclear envelope pore membrane protein POM 121A) (Nucleoporin Nup121) (Pore membrane protein of 121 kDa)

Gene: P121A, POM121
Organism: Homo sapiens
Interactions: 159
UniProt ID: Q96HA1

Gene Ontology (top 5):
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0005654 - nucleoplasm
GO:0005789 - endoplasmic reticulum membrane
GO:0006405 - RNA export from nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

386094

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

5

16

High-throughput

0.702

High

938125

ANM2
Protein arginine N-methyltransferase 2

4

5

High-throughput

0.691

High

1391479

BSCL2
Seipin

4

1

High-throughput

0.691

High

683505

IKBA
NF-kappa-B inhibitor alpha

3

13

High-throughput

0.667

High

1392803

G3BP2
Ras GTPase-activating protein-binding protein 2

3

4

High-throughput

0.667

High

1392779

JPH4
Junctophilin-4

3

1

High-throughput

0.662

High

353500

AGR2
Anterior gradient protein 2 homolog

4

3

High-throughput

0.644

High

900459

FXR2
RNA-binding protein FXR2

2

16

High-throughput

0.640

High

158583

CTDS2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

3

0

High-throughput

0.638

High

138745

IMA4
Importin subunit alpha-4

2

15

High-throughput

0.628

High

142603

IMA3
Importin subunit alpha-3

2

15

High-throughput

0.628

High

749800

CADH5
Cadherin-5

2

8

High-throughput

0.628

High

1134327

IMB1
Importin subunit beta-1

2

16

High-throughput

0.628

High

1359346

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

2

7

High-throughput

0.628

High

927484

ATX1
Ataxin-1

2

4

High-throughput

0.628

High

1372028

RBPMS
RNA-binding protein with multiple splicing

2

0

High-throughput

0.618

High

1392790

HOME3
Homer protein homolog 3

3

4

High-throughput

0.616

High

253978

LPXN
Leupaxin

3

15

High-throughput

0.609

High

783372

TRI23
E3 ubiquitin-protein ligase TRIM23

3

1

High-throughput

0.609

High

989078

AP2B1
AP-2 complex subunit beta

3

7

High-throughput

0.609

High

1063521

GOGA2
Golgin subfamily A member 2

3

9

High-throughput

0.609

High

1151618

TRIP6
Thyroid receptor-interacting protein 6

3

10

High-throughput

0.609

High

212469

SPIT2
Kunitz-type protease inhibitor 2

3

5

High-throughput

0.609

High

627556

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

3

3

High-throughput

0.609

High

787577

TNR3
Tumor necrosis factor receptor superfamily member 3

3

5

High-throughput

0.609

High

1249955

I20RB
Interleukin-20 receptor subunit beta

3

1

High-throughput

0.609

High

1392796

ACHA9
Neuronal acetylcholine receptor subunit alpha-9

3

3

High-throughput

0.609

High

253676

IMA7
Importin subunit alpha-7

2

15

High-throughput

0.606

High

572134

TRI27
Zinc finger protein RFP

2

6

High-throughput

0.606

High

827892

STAT3
Signal transducer and activator of transcription 3

2

4

High-throughput

0.606

High

1090851

TRAF2
TNF receptor-associated factor 2

2

12

High-throughput

0.606

High

1197859

S39AC
Zinc transporter ZIP12

3

6

High-throughput

0.604

High

548090

PSPC
Surfactant protein C

2

1

High-throughput

0.601

High

1110533

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

2

7

High-throughput

0.601

High

1338895

NUP43
Nucleoporin Nup43

2

20

High-throughput

0.584

High

1339134

NUP35
Nucleoporin NUP35

2

6

High-throughput

0.584

High

1392792

TFP11
Tuftelin-interacting protein 11

2

0

High-throughput

0.580

High

62152

KLRG2
Killer cell lectin-like receptor subfamily G member 2

2

5

High-throughput

0.574

High

1392789

PCDBG
Protocadherin beta-16

2

8

High-throughput

0.574

High

1257100

PAXI1
PAX-interacting protein 1

1

16

High-throughput

0.573

High

505894

JMJD7
Bifunctional peptidase and

2

1

High-throughput

0.553

High

509965

TRI49
Tripartite motif-containing protein 49

2

5

High-throughput

0.553

High

820718

CEAM6
Cell adhesion molecule CEACAM6

2

1

High-throughput

0.553

High

1083294

AP1B1
AP-1 complex subunit beta-1

2

7

High-throughput

0.553

High

1094956

TRAF3
TNF receptor-associated factor 3

2

17

High-throughput

0.553

High

1180005

CCD57
Coiled-coil domain-containing protein 57

2

9

High-throughput

0.553

High

1219579

MORN5
MORN repeat-containing protein 5

2

1

High-throughput

0.553

High

1273058

OTU6A
OTU domain-containing protein 6A

2

2

High-throughput

0.553

High

1332298

BOLL
Protein boule-like

2

7

High-throughput

0.553

High

1392782

SPAG5
Sperm-associated antigen 5

2

17

High-throughput

0.553

High

1392797

UBQL2
Ubiquilin-2

2

1

High-throughput

0.553

High

1392813

MAGD1
Melanoma-associated antigen D1

2

4

High-throughput

0.553

High

1392781

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

7

High-throughput

0.549

High

668690

APC
Adenomatous polyposis coli protein

1

15

High-throughput

0.541

High

1392812

CERT
Ceramide transfer protein

1

4

High-throughput

0.541

High

49537

SHSA3
Protein shisa-3 homolog

1

1

High-throughput

0.536

High

134121

IPO5
Importin-5

1

15

High-throughput

0.536

High

595095

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

7

High-throughput

0.536

High

890386

NU153
Nuclear pore complex protein Nup153

1

19

High-throughput

0.536

High

911050

IMA1
Importin subunit alpha-1

1

15

High-throughput

0.536

High

1085365

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

13

High-throughput

0.536

High

1110286

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

7

High-throughput

0.536

High

1115903

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

11

High-throughput

0.536

High

1126341

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

1

High-throughput

0.536

High

1180952

HFE
Hereditary hemochromatosis protein

1

1

High-throughput

0.536

High

1392784

TCAB1
Telomerase Cajal body protein 1

1

17

High-throughput

0.536

High

1198741

MPPE1
Metallophosphoesterase 1

1

0

High-throughput

0.513

High

1392805

TMED7
Transmembrane emp24 domain-containing protein 7

1

0

High-throughput

0.513

High

570557

GFAP
Glial fibrillary acidic protein

1

4

High-throughput

0.494

High

270168

LRP3
Low-density lipoprotein receptor-related protein 3

1

2

High-throughput

0.489

High

349532

TSN15
Tetraspanin-15

1

1

High-throughput

0.489

High

380473

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

4

High-throughput

0.489

High

539734

ACHB
Acetylcholine receptor subunit beta

1

3

High-throughput

0.489

High

607972

ACHB2
Neuronal acetylcholine receptor subunit beta-2

1

3

High-throughput

0.489

High

648791

KCNA4
Potassium voltage-gated channel subfamily A member 4

1

7

High-throughput

0.489

High

838503

GRIA2
Glutamate receptor 2

1

6

High-throughput

0.489

High

1022451

IDD
Integral membrane protein DGCR2/IDD

1

2

High-throughput

0.489

High

1057109

FMOD
Fibromodulin

1

2

High-throughput

0.489

High

1116561

FHL3
Four and a half LIM domains protein 3

1

11

High-throughput

0.489

High

1203765

TTMP
TPA-induced transmembrane protein

1

1

High-throughput

0.489

High

1213675

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

3

High-throughput

0.489

High

1249729

AEGP
Apical endosomal glycoprotein

1

5

High-throughput

0.489

High

1249830

BTNL9
Butyrophilin-like protein 9

1

5

High-throughput

0.489

High

1392787

TTYH1
Protein tweety homolog 1

1

1

High-throughput

0.489

High

1392791

EVA1B
Protein eva-1 homolog B

1

1

High-throughput

0.489

High

1392793

DKK3
Dickkopf-related protein 3

1

1

High-throughput

0.489

High

1392795

FBLN5
Fibulin-5

1

3

High-throughput

0.489

High

1392802

PCDGG
Protocadherin gamma-B4

1

8

High-throughput

0.489

High

1392808

PCDB3
Protocadherin beta-3

1

8

High-throughput

0.489

High

1392809

PCDGL
Protocadherin gamma-C4

1

7

High-throughput

0.489

High

1392810

PCDGH
Protocadherin gamma-B5

1

8

High-throughput

0.489

High

1392811

PCDG4
Protocadherin gamma-A4

1

8

High-throughput

0.489

High

190022

TOX3
TOX high mobility group box family member 3

1

14

High-throughput

0.481

High

799389

BRCA1
Breast cancer type 1 susceptibility protein

1

15

High-throughput

0.481

High

135313

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

8

High-throughput

0.479

High

291485

NU155
Nuclear pore complex protein Nup155

1

8

High-throughput

0.479

High

634577

LMNB1
Lamin-B1

1

16

High-throughput

0.479

High

831238

CCNF
Cyclin-F

1

6

High-throughput

0.479

High

894970

EMD
Emerin

1

4

High-throughput

0.479

High

951349

SC61B
Protein transport protein Sec61 subunit beta

1

3

High-throughput

0.479

High

1048060

TLE3
Transducin-like enhancer protein 3

1

16

High-throughput

0.479

High

1085266

NU160
Nuclear pore complex protein Nup160

1

2

High-throughput

0.479

High

1229035

RNF43
E3 ubiquitin-protein ligase RNF43

1

9

High-throughput

0.479

High

1249112

LMBRL
Protein LMBR1L

1

3

High-throughput

0.479

High

1329808

SIR6
NAD-dependent protein deacylase sirtuin-6

1

11

High-throughput

0.479

High

1356922

NU133
Nuclear pore complex protein Nup133

1

4

High-throughput

0.479

High

1387488

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

20

High-throughput

0.479

High

1392785

NUP85
Nuclear pore complex protein Nup85

1

4

High-throughput

0.479

High

1392794

NXF1
Nuclear RNA export factor 1

1

7

High-throughput

0.479

High

1392799

XPO7
Exportin-7

1

12

High-throughput

0.479

High

1392800

NUP50
Nuclear pore complex protein Nup50

1

10

High-throughput

0.479

High

1392806

TRRAP
Transformation/transcription domain-associated protein

1

6

High-throughput

0.479

High

1392783

CGRF1
Cell growth regulator with RING finger domain protein 1

1

0

High-throughput

0.458

High

938266

SEC13
Protein SEC13 homolog

1

20

Small-scale

0.457

High

1276144

NUP54
Nucleoporin p54

1

11

Small-scale

0.457

High

702151

ITPI2
Protein ITPRID2

1

1

High-throughput

0.445

High

911339

IMA5
Importin subunit alpha-5

1

15

High-throughput

0.445

High

964708

DCAF7
DDB1- and CUL4-associated factor 7

1

13

High-throughput

0.445

High

1047690

NOTC2
Neurogenic locus notch homolog protein 2

1

3

High-throughput

0.445

High

1110392

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

7

High-throughput

0.445

High

1367013

ESR2
Estrogen receptor beta

1

20

High-throughput

0.445

High

1392798

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

3

High-throughput

0.445

High

272385

OBSL1
Obscurin-like protein 1

1

7

High-throughput

0.437

High

365448

PGK1
Phosphoglycerate kinase 1

1

1

High-throughput

0.437

High

456000

ASGR2
Asialoglycoprotein receptor 2

1

4

High-throughput

0.437

High

946582

EVA1C
Protein eva-1 homolog C

1

1

High-throughput

0.437

High

1010089

DLK1
Protein delta homolog 1

1

1

High-throughput

0.437

High

1197539

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

14

High-throughput

0.437

High

1255058

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.437

High

1276636

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

15

High-throughput

0.437

High

1384243

SH3K1
SH3 domain-containing kinase-binding protein 1

1

9

High-throughput

0.437

High

1392807

MARF1
Meiosis regulator and mRNA stability factor 1

1

1

High-throughput

0.437

High

1335677

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.426

High

380576

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

4

High-throughput

0.407

High

1133798

SL9A5
Sodium/hydrogen exchanger 5

1

2

High-throughput

0.407

High

1152202

MARE1
Microtubule-associated protein RP/EB family member 1

1

8

High-throughput

0.407

High

1313795

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.407

High

1392801

PNMA2
Paraneoplastic antigen Ma2

1

2

High-throughput

0.407

High

1347440

CEP76
Centrosomal protein of 76 kDa

3

0

High-throughput

0.352

High

1314983

TEX11
Testis-expressed protein 11

2

0

High-throughput

0.337

High

191973

TEX28
Testis-specific protein TEX28

2

0

High-throughput

0.328

High

1308416

UN5CL
UNC5C-like protein

2

0

High-throughput

0.328

High

50347

F168B
Myelin-associated neurite-outgrowth inhibitor

2

0

High-throughput

0.316

High

1392786

ZMY12
Zinc finger MYND domain-containing protein 12

2

0

High-throughput

0.316

High

1392804

COG6
Conserved oligomeric Golgi complex subunit 6

2

0

High-throughput

0.316

High

1392814

KCNE3
Potassium voltage-gated channel subfamily E member 3

2

0

High-throughput

0.313

High

863423

GLYG
Glycogenin-1

1

0

High-throughput

0.282

High

1198493

CEP55
Centrosomal protein of 55 kDa

1

0

High-throughput

0.282

High

219349

B4GA1
Beta-1,4-glucuronyltransferase 1

1

0

High-throughput

0.279

Low

518892

CCL3
C-C motif chemokine 3

1

0

High-throughput

0.279

Low

596520

CTLA4
Cytotoxic T-lymphocyte protein 4

1

0

High-throughput

0.279

Low

1325157

TM130
Transmembrane protein 130

1

0

High-throughput

0.279

Low

1361956

BSND
Barttin

1

0

High-throughput

0.279

Low

1392778

TM169
Transmembrane protein 169

1

0

High-throughput

0.279

Low

1392780

OPALI
Opalin

1

0

High-throughput

0.279

Low

1392788

MANS1
MANSC domain-containing protein 1

1

0

High-throughput

0.279

Low

337008

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

0

Small-scale

0.249

Low

914467

EFNB2
Ephrin-B2

1

0

High-throughput

0.249

Low

1357036

S20A1
Sodium-dependent phosphate transporter 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025