HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: S12A6 (Q9UHW9)
Solute carrier family 12 member 6 (Electroneutral potassium-chloride cotransporter 3) (K-Cl cotransporter 3)
Gene: SLC12A6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001525 - angiogenesis GO:0005886 - plasma membrane GO:0019901 - protein kinase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 1150
+	Hs
		925735 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		S12A4_HUMAN (100-1150): 0: 1096: 77.68
+	Hs
		901055 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		S12A4_HUMAN (100-1150): 0: 1096: 77.68
+	Hs
		916077 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		S12A4_HUMAN (100-1150): 0: 1096: 77.68
+	Hs
		925769 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		S12A7_HUMAN (71-1150): 0: 1064: 69.37
+	Hs
		916106 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		S12A7_HUMAN (71-1150): 0: 1064: 69.37
+	Hs
		873903 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		S12A2_HUMAN (4-1150): 0: 719: 19.32
+	Hs
		873898 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		S12A2_HUMAN (4-1150): 0: 719: 19.32
+	Hs
		873902 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		S12A2_HUMAN (4-1150): 0: 719: 19.32
+	Hs
		854874 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		CTR2_HUMAN (229-668): 4.31e-92: 311: 15.46
+	Hs
		854869 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		CTR2_HUMAN (229-668): 4.31e-92: 311: 15.46
+	Hs
		854873 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		CTR2_HUMAN (229-668): 4.31e-92: 311: 15.46
+	Hs
		676533 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		CTR1_HUMAN (231-668): 3.36e-86: 294: 13.90
+	Hs
		676530 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		CTR1_HUMAN (231-668): 3.36e-86: 294: 13.90
+	Hs
		676532 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		CTR1_HUMAN (231-668): 3.36e-86: 294: 13.90
+	Hs
		925480 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		YLAT2_HUMAN (233-744): 9.04e-82: 278: 10.14
+	Hs
		900749 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		YLAT2_HUMAN (233-744): 9.04e-82: 278: 10.14
+	Hs
		915871 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		YLAT2_HUMAN (233-744): 9.04e-82: 278: 10.14
+	Hs
		925205 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		LAT1_HUMAN (231-752): 6.68e-80: 273: 12.08
+	Hs
		900388 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		LAT1_HUMAN (231-752): 6.68e-80: 273: 12.08
+	Hs
		915614 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		LAT1_HUMAN (231-752): 6.68e-80: 273: 12.08