HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: USF2 (Q15853)
Upstream stimulatory factor 2 (Class B basic helix-loop-helix protein 12) (bHLHb12) (FOS-interacting protein) (FIP) (Major late transcription factor 2) (Upstream transcription factor 2)
Gene: USF2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0046982 - protein heterodimerization activity
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 346
+	Hs
		607804 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		USF1_HUMAN (22-340): 2.39e-74: 233: 48.81
+	Hs
		917953 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MLXIP_HUMAN (102-346): 6.29e-39: 149: 18.85
+	Hs
		917972 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MLXPL_HUMAN (88-346): 3.5e-38: 146: 17.79
+	Mm
		918249 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		TFE3_MOUSE (102-339): 5.26e-35: 136: 24.40
+	Hs
		585646 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		TFE3_HUMAN (102-339): 9.04e-34: 132: 24.00
+	Hs
		252913 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MITF_HUMAN (102-338): 1.95e-31: 125: 18.21
+	Hs
		585112 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		TFEB_HUMAN (104-341): 1.85e-31: 125: 19.67
+	Sc
		356426 H4_YEAST (18-103): 6.13e-41: 132: 90.70		RTG3_YEAST (43-337): 6.08e-38: 143: 18.35
+	Mm
		348414 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		MYC_MOUSE (115-326): 7.07e-31: 123: 18.61
+	Hs
		346438 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MYC_HUMAN (115-326): 5.58e-30: 120: 19.54
+	Hs
		738952 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		SRBP1_HUMAN (101-345): 3.08e-27: 114: 17.11
+	Hs
		918090 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MLX_HUMAN (121-335): 2.85e-28: 113: 18.78
+	Hs
		917430 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		USF3_HUMAN (220-346): 2.47e-22: 100: 26.56
+	Hs
		379230 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MYCN_HUMAN (136-324): 9.83e-22: 97.5: 15.87
+	Hs
		898095 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MAX_HUMAN (223-335): 3.67e-22: 93.1: 31.86
+	Hs
		379768 H4G_HUMAN (1-98): 1.04e-38: 126: 84.69		MYCN_HUMAN (136-324): 9.83e-22: 97.5: 15.87