HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: H3C (Q6NXT2)
Histone H3.3C (Histone H3.5)
Gene: H3-5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CENP-T_C~Histone
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 135
+	Hs
		917093 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H31_HUMAN (1-135): 4.22e-57: 175: 92.65
+	Mm
		918236 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		H31_MOUSE (1-135): 4.22e-57: 175: 92.65
+	Hs
		917112 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H33_HUMAN (1-135): 1.39e-56: 174: 94.85
+	Mm
		918240 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		H33_MOUSE (1-135): 1.39e-56: 174: 94.85
+	Xl
		917056 H4_XENLA (1-103): 1.38e-48: 151: 100.00		Q92133_XENLA (1-135): 3.46e-56: 173: 92.65
+	Hs
		917352 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H31T_HUMAN (1-135): 2.09e-56: 173: 89.71
+	Ce
		445733 H4_CAEEL (1-103): 1.41e-48: 151: 99.03		H3_CAEEL (1-135): 9.37e-56: 172: 90.44
+	Xl
		917054 H4_XENLA (1-103): 1.38e-48: 151: 100.00		H32_XENLA (1-135): 5.98e-56: 172: 93.38
+	Hs
		917483 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H32_HUMAN (1-135): 5.98e-56: 172: 93.38
+	Mm
		918239 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		H32_MOUSE (1-135): 5.98e-56: 172: 93.38
+	Sp
		448920 H4_SCHPO (18-103): 4.87e-42: 135: 89.54		H31_SCHPO (1-135): 2.06e-54: 168: 86.77
+	Hs
		1174638 H4G_HUMAN (1-98): 1.04e-38: 126: 84.69		H32_HUMAN (1-135): 5.98e-56: 172: 93.38
+	Sc
		356652 H4_YEAST (18-103): 6.13e-41: 132: 90.70		H3_YEAST (1-135): 4.1e-51: 160: 85.29
+	Ce
		711990 H4_CAEEL (1-103): 1.41e-48: 151: 99.03		HCP3L_CAEEL (8-130): 1.92e-40: 137: 44.28
+	Hs
		828186 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CENPA_HUMAN (9-132): 2.48e-39: 130: 47.69
+	Sc
		356401 H4_YEAST (18-103): 6.13e-41: 132: 90.70		CENPA_YEAST (8-133): 2.36e-44: 146: 54.26
+	Kl
		1150023 Q6CMU6_KLULA (18-103): 9.41e-42: 134: 91.86		CENPA_KLULA (40-133): 1.54e-41: 137: 65.98