HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: H2A1H (Q96KK5)
Histone H2A type 1-H (H2A-clustered histone 12) (Histone H2A/s)
Gene: H2AC12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30021884
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CENP-T_C~Histone, CENP-T_C~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity GO:0070062 - extracellular exosome
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 128
+	Hs
		917438 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2A2A_HUMAN (1-128): 4.68e-67: 200: 98.44
+	Hs
		917817 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2A1J_HUMAN (1-128): 2.71e-67: 200: 99.22
+	Hs
		391638 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2A1B_HUMAN (1-128): 1.07e-66: 199: 98.44
+	Hs
		470324 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2A1_HUMAN (1-128): 6.72e-67: 199: 100.00
+	Hs
		594838 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2A1D_HUMAN (1-128): 7.84e-67: 199: 99.22
+	Hs
		917496 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2A3_HUMAN (1-128): 7.5e-67: 199: 97.66
+	Hs
		917699 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2A1C_HUMAN (1-128): 6.95e-67: 199: 98.44
+	Hs
		917544 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2A2B_HUMAN (1-128): 1.07e-65: 196: 95.31
+	Hs
		917354 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2A2C_HUMAN (1-124): 8.56e-65: 194: 98.39
+	Hs
		555395 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2AX_HUMAN (1-124): 2.04e-63: 191: 94.36
+	Dm
		950379 H4_DROME (1-103): 4.51e-48: 150: 99.03		H2A_DROME (17-125): 5.6e-59: 179: 89.91
+	Sc
		356148 H4_YEAST (18-103): 6.13e-41: 132: 90.70		H2A2_YEAST (16-127): 1.11e-58: 179: 81.25
+	Sc
		356147 H4_YEAST (18-103): 6.13e-41: 132: 90.70		H2A1_YEAST (16-127): 3.38e-53: 165: 81.25