Protein: XRCC4
Non-homologous end-joining factor LIF1 (Ligase-interacting factor 1)

Gene: XRCC4, LIF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 22
UniProt ID: P53150

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006303 - double-strand break repair via nonhomologous end joining

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

917755

DNLI4
DNA ligase 4

14

0

Small-scale

0.730

High

917752

NHEJ1
Non-homologous end-joining protein 1

12

0

Small-scale

0.727

High

751050

XRS2
DNA repair protein XRS2

6

0

Small-scale

0.702

High

917753

SP382
Pre-mRNA-splicing factor SPP382

4

0

Small-scale

0.659

High

622983

CSK22
Casein kinase II subunit alpha'

2

0

Small-scale

0.576

High

718952

CGS5
S-phase entry cyclin-5

1

0

High-throughput

0.513

High

792362

AHP1
Peroxiredoxin AHP1

1

0

High-throughput

0.513

High

917750

MEC3
DNA damage checkpoint control protein MEC3

1

0

High-throughput

0.513

High

917751

SIZ1
E3 SUMO-protein ligase SIZ1

1

1

Small-scale

0.501

High

917757

SIZ2
E3 SUMO-protein ligase SIZ2

1

1

Small-scale

0.501

High

818691

GPP2
Glycerol-1-phosphate phosphohydrolase 2

1

0

High-throughput

0.493

High

700027

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

0

High-throughput

0.486

High

814237

RV167
Reduced viability upon starvation protein 167

1

0

High-throughput

0.486

High

364656

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.480

High

917748

XRCC4
Non-homologous end-joining factor LIF1

1

0

Small-scale

0.460

High

781950

KAE1
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.458

High

917756

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.458

High

819319

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.426

High

917749

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

368717

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.261

Low

917754

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025