HitPredict

Interactor 1: RAN (P62826)
GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)
Gene: RAN

Interactor 2: ZRAN1 (Q9UGI0)
Ubiquitin thioesterase ZRANB1 (EC 3.4.19.12) (TRAF-binding domain-containing protein) (hTrabid) (Zinc finger Ran-binding domain-containing protein 1)
Gene: ZRANB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35944360
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~zf-RanBP
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 216 Hs			1 708
+	Hs
		1070438 RAB35_HUMAN (6-188): 1.31e-87: 258: 29.19		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		918961 RAB1A_HUMAN (1-196): 3.67e-82: 244: 28.00		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1328154 RAB1B_HUMAN (4-195): 1.12e-80: 240: 28.72		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		894822 RAB8A_HUMAN (1-203): 1.27e-79: 238: 24.76		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		914431 RB11A_HUMAN (4-207): 7.68e-78: 234: 25.94		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		895562 RAB10_HUMAN (11-177): 3.9e-29: 109: 33.14		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		845324 RAB7A_HUMAN (8-166): 7.44e-29: 108: 33.13		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		919124 RAN_HUMAN (1-216): 7.75e-79: 237: 100.00		OTU7B_HUMAN (322-701): 2.32e-127: 400: 25.54
+	Zm
		37867 A0A1D6MDI8_MAIZE (11-197): 3.08e-109: 314: 74.26		C0HH86_MAIZE (4-112): 1.02e-10: 66.9: 18.75
+	Hs
		834710 RAN_HUMAN (1-216): 7.75e-79: 237: 100.00		RBP2_HUMAN (35-380): 3.46e-21: 101: 9.86
+	Hs
		834576 RAN_HUMAN (1-216): 7.75e-79: 237: 100.00		NU153_HUMAN (109-348): 5.07e-09: 61.9: 11.11