Protein: APP1
Phosphatidate phosphatase APP1 (PAP) (EC 3.1.3.4) (Actin patch protein 1)

Gene: APP1
Organism: Saccharomyces cerevisiae S288C
Interactions: 55
UniProt ID: P53933

Gene Ontology (top 5):
GO:0006629 - lipid metabolic process
GO:0008195 - phosphatidate phosphatase activity
GO:0030479 - actin cortical patch

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

814248

RV167
Reduced viability upon starvation protein 167

7

5

Small-scale

0.749

High

587327

ABP1
Actin-binding protein

8

0

Small-scale

0.726

High

850459

LSB3
LAS seventeen-binding protein 3

4

2

High-throughput

0.707

High

745028

YSC84
Protein YSC84

3

3

High-throughput

0.678

High

805419

BZZ1
Protein BZZ1

3

0

High-throughput

0.654

High

924927

PIN3
[PSI+] inducibility protein 3

2

2

High-throughput

0.632

High

744901

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

2

0

High-throughput

0.609

High

864735

BBC1
Myosin tail region-interacting protein MTI1

2

0

High-throughput

0.609

High

919297

LSB1
LAS seventeen-binding protein 1

2

3

High-throughput

0.605

High

924924

MYO5
Myosin-5

2

1

High-throughput

0.586

High

751867

SLA2
Protein SLA2

2

0

High-throughput

0.565

High

924926

CORO
Coronin-like protein

2

0

High-throughput

0.565

High

924925

CYK2
Cytokinesis protein 2

1

2

High-throughput

0.518

High

924921

COFI
Cofilin

1

0

High-throughput

0.513

High

672335

RV161
Reduced viability upon starvation protein 161

1

1

Small-scale

0.508

High

779010

MYO3
Myosin-3

1

1

High-throughput

0.501

High

798424

RGD1
RHO GTPase-activating protein RGD1

1

0

High-throughput

0.486

High

924919

ACT
Actin

1

0

High-throughput

0.479

High

924931

LAS17
Proline-rich protein LAS17

1

0

Small-scale

0.458

High

813777

AIM2
Protein AIM2

2

0

High-throughput

0.314

High

867856

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

2

0

High-throughput

0.314

High

924929

NBP2
NAP1-binding protein 2

2

0

High-throughput

0.310

High

748888

SWE1
Mitosis inhibitor protein kinase SWE1

2

0

High-throughput

0.307

High

794695

SRO77
Lethal(2) giant larvae protein homolog SRO77

2

0

High-throughput

0.307

High

797249

HSL7
Protein arginine N-methyltransferase HSL7

2

0

High-throughput

0.307

High

924920

PEX13
Peroxisomal membrane protein PEX13

1

0

High-throughput

0.296

High

803369

HSE1
Class E vacuolar protein-sorting machinery protein HSE1

1

0

High-throughput

0.282

High

575986

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.279

Low

604969

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

788425

PGM2
Phosphoglucomutase 2

1

0

High-throughput

0.279

Low

863162

FYV8
Protein FYV8

1

0

High-throughput

0.279

Low

924922

OYE2
NADPH dehydrogenase 2

1

0

High-throughput

0.279

Low

924930

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

0

High-throughput

0.279

Low

825999

ACA2
ATF/CREB activator 2

1

0

High-throughput

0.269

Low

553926

WHI2
Growth regulation protein

1

0

High-throughput

0.265

Low

656576

KC11
Casein kinase I homolog 1

1

0

High-throughput

0.261

Low

850958

TOS3
Serine/threonine-protein kinase TOS3

1

0

High-throughput

0.261

Low

917145

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.261

Low

924928

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.261

Low

367090

ATPB
ATP synthase subunit beta, mitochondrial

1

0

High-throughput

0.261

Low

405126

LEU3
3-isopropylmalate dehydrogenase

1

0

High-throughput

0.261

Low

425141

OTC
Ornithine carbamoyltransferase

1

0

High-throughput

0.261

Low

621392

METK2
S-adenosylmethionine synthase 2

1

0

High-throughput

0.261

Low

626844

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.261

Low

709912

BMH1
Protein BMH1

1

0

High-throughput

0.261

Low

801888

KSP1
Serine/threonine-protein kinase KSP1

1

0

High-throughput

0.261

Low

707854

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

747982

SMY2
Protein SMY2

1

0

High-throughput

0.249

Low

574912

SAM35
Sorting assembly machinery 35 kDa subunit

1

0

High-throughput

0.238

Low

809280

MET30
F-box protein MET30

1

0

High-throughput

0.238

Low

874366

RAD17
DNA damage checkpoint control protein RAD17

1

0

High-throughput

0.238

Low

924923

PRP42
U1 small nuclear ribonucleoprotein component PRP42

1

0

High-throughput

0.238

Low

510712

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.232

Low

524790

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.232

Low

545844

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025