HitPredict

Interactor 1: UB2D2 (P62837)
Ubiquitin-conjugating enzyme E2 D2 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D2) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2) (p53-regulated ubiquitin-conjugating enzyme 1)
Gene: UBE2D2

Interactor 2: TRI10 (Q9UDY6)
Tripartite motif-containing protein 10 (B30-RING finger protein) (RING finger protein 9)
Gene: TRIM10

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	21143188
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4
Common GO terms	GO:0016567 - protein ubiquitination GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Hs			1 481
+	Hs
		1336390 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI39_HUMAN (7-479): 1.3e-142: 420: 34.51
+	Hs
		537142 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI27_HUMAN (1-480): 1.66e-142: 420: 33.27
+	Hs
		584923 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		RO52_HUMAN (1-480): 1.33e-143: 421: 30.74
+	Hs
		536779 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI27_HUMAN (1-480): 1.66e-142: 420: 33.27
+	Hs
		1354526 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI10_HUMAN (1-481): 6.89e-138: 407: 100.00
+	Hs
		919822 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI11_HUMAN (1-480): 3.26e-137: 405: 30.91
+	Mm
		919925 UB2D2_MOUSE (1-147): 9.5e-83: 241: 100.00		TRI17_MOUSE (1-475): 1.89e-128: 383: 27.95
+	Hs
		135045 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI38_HUMAN (1-471): 2.52e-123: 369: 30.74
+	Hs
		135019 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI38_HUMAN (1-471): 2.52e-123: 369: 30.74
+	Hs
		1377469 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI17_HUMAN (1-475): 1.72e-121: 365: 26.50
+	Hs
		1204911 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI50_HUMAN (1-472): 1.03e-118: 358: 25.63
+	Hs
		919773 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI50_HUMAN (1-472): 1.03e-118: 358: 25.63
+	Hs
		1318719 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRIM5_HUMAN (1-481): 4.06e-116: 352: 26.14
+	Hs
		1313765 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI62_HUMAN (9-479): 1.4e-111: 339: 23.96
+	Hs
		1285831 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI43_HUMAN (1-472): 3.34e-107: 327: 24.63
+	Hs
		919816 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI43_HUMAN (1-472): 3.34e-107: 327: 24.63
+	Hs
		1318532 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI31_HUMAN (1-301): 3.69e-48: 172: 32.56
+	Hs
		1357712 UB2D4_HUMAN (1-147): 2.21e-83: 243: 93.20		TRI35_HUMAN (9-475): 5.94e-34: 135: 27.35
+	Hs
		919712 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI26_HUMAN (379-479): 1.75e-33: 134: 50.50
+	Hs
		919800 UB2D2_HUMAN (1-147): 9.5e-83: 241: 100.00		TRI41_HUMAN (1-44): 1.45e-10: 65.7: 43.75