Interactor 1: GBB1 (P62871)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Interactor 2: GBG2 (P63212)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 (G gamma-I)
Gene: GNG2

Species: Bos taurus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.761

The method score is based on:

Property Details
Experiments 20018744
Identification Methods ion exchange chromatography, molecular sieving, dynamic light scattering, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains G-gamma~WD40
Common GO terms GO:0005834 - heterotrimeric G-protein complex
GO:0007186 - G protein-coupled receptor signaling pathway
GO:0007191 - adenylate cyclase-activating dopamine receptor signaling pathway
GO:0016020 - membrane
GO:0071380 - cellular response to prostaglandin E stimulus
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 340
Bt

1 71
+ Hs
+ Hs
+ Mm
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+ Hs
+ Hs
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+ Hs
+ Hs
+ Hs
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+ Bt
+ Hs
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+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024