Protein: CO5A1
Collagen alpha-1(V) chain

Gene: CO5A1, COL5A1
Organism: Homo sapiens
Interactions: 61
UniProt ID: P20908

Gene Ontology (top 5):
GO:0001568 - blood vessel development
GO:0005588 - collagen type V trimer
GO:0003007 - heart morphogenesis
GO:0005178 - integrin binding
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

635467

C1QT2
Complement C1q tumor necrosis factor-related protein 2

3

20

High-throughput

0.861

High

635445

CO8A2
Collagen alpha-2(VIII) chain

3

19

High-throughput

0.847

High

635466

C1QT1
Complement C1q tumor necrosis factor-related protein 1

2

20

High-throughput

0.776

High

635455

PCOC1
Procollagen C-endopeptidase enhancer 1

1

2

Small-scale

0.713

High

469662

MMP2
72 kDa type IV collagenase

4

20

Small-scale

0.693

High

388766

C1QC
Complement C1q subcomponent subunit C

1

20

High-throughput

0.691

High

635446

CO8A1
Collagen alpha-1(VIII) chain

1

19

High-throughput

0.691

High

562694

BMP1
Bone morphogenetic protein 1

1

2

Small-scale

0.681

High

607526

PTN2
Tyrosine-protein phosphatase non-receptor type 2

3

2

High-throughput

0.657

High

575778

MMP9
Matrix metalloproteinase-9

2

20

High-throughput

0.628

High

635450

PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

2

20

High-throughput

0.628

High

326237

PRS23
Serine protease 23

2

0

High-throughput

0.602

High

635459

LAIR2
Leukocyte-associated immunoglobulin-like receptor 2

2

15

High-throughput

0.601

High

384107

CO1A1
Collagen alpha-1(I) chain

1

17

Small-scale

0.590

High

465937

CO1A2
Collagen alpha-2(I) chain

1

13

Small-scale

0.590

High

551757

CO6A1

1

18

Small-scale

0.590

High

551837

CO6A2

1

19

Small-scale

0.590

High

551905

CO6A3

1

19

Small-scale

0.590

High

635451

COAA1

1

19

High-throughput

0.575

High

635458

Q4VAQ0
COL8A2 protein

1

20

High-throughput

0.575

High

376374

PDGFB
Platelet-derived growth factor subunit B

1

11

Small-scale

0.536

High

635443

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

4

High-throughput

0.536

High

370003

TIMP1
Metalloproteinase inhibitor 1

1

7

Small-scale

0.506

High

389022

FINC
Fibronectin

1

20

Small-scale

0.506

High

635444

TENA
Tenascin

1

6

Small-scale

0.506

High

403064

PDGFA
Platelet-derived growth factor subunit A

1

11

Small-scale

0.501

High

464416

TSP1
Thrombospondin-1

1

8

Small-scale

0.501

High

482670

SPRC
SPARC

1

5

Small-scale

0.501

High

635442

MAG
Myelin-associated glycoprotein

1

5

Small-scale

0.501

High

610983

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

2

High-throughput

0.489

High

625192

CSK22
Casein kinase II subunit alpha'

1

1

High-throughput

0.489

High

635447

BMI1
Polycomb complex protein BMI-1

1

2

High-throughput

0.489

High

217822

TGON2
Trans-Golgi network integral membrane protein 2

1

7

High-throughput

0.479

High

468060

HS90B
Heat shock protein HSP 90-beta

1

3

High-throughput

0.479

High

590796

TIMP2
Metalloproteinase inhibitor 2

1

7

High-throughput

0.479

High

635449

H11
Histone H1.1

1

7

High-throughput

0.479

High

635473

ATS5
A disintegrin and metalloproteinase with thrombospondin motifs 5

1

1

High-throughput

0.479

High

128773

MEN1
Menin

1

0

High-throughput

0.458

High

635471

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.458

High

191292

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

11

High-throughput

0.445

High

251856

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

1

20

High-throughput

0.445

High

635457

P3H1
Prolyl 3-hydroxylase 1

1

3

High-throughput

0.445

High

635461

GALT7
N-acetylgalactosaminyltransferase 7

1

0

Small-scale

0.438

High

521535

H14
Histone H1.4

1

7

High-throughput

0.437

High

595313

H15
Histone H1.5

1

7

High-throughput

0.437

High

595680

H13
Histone H1.3

1

7

High-throughput

0.437

High

595933

H12
Histone H1.2

1

7

High-throughput

0.437

High

635454

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.437

High

635468

CHM4B
Charged multivesicular body protein 4b

1

3

High-throughput

0.437

High

635469

ECT2
Protein ECT2

1

3

High-throughput

0.437

High

635470

ANLN
Anillin

1

2

High-throughput

0.437

High

635465

KLH15
Kelch-like protein 15

1

19

High-throughput

0.407

High

635453

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.279

Low

635462

SUGP2
SURP and G-patch domain-containing protein 2

1

0

High-throughput

0.269

Low

635448

KIF23
Kinesin-like protein KIF23

1

0

High-throughput

0.249

Low

635456

E2F4
Transcription factor E2F4

1

0

High-throughput

0.249

Low

635460

OFUT3
GDP-fucose protein O-fucosyltransferase 3

1

0

High-throughput

0.249

Low

635464

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.249

Low

635472

T106B
Transmembrane protein 106B

1

0

High-throughput

0.249

Low

635452

ECHP
Peroxisomal bifunctional enzyme

1

0

High-throughput

0.232

Low

635463

MSPD2
Motile sperm domain-containing protein 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025