HitPredict

Interactor 1: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Interactor 2: TBB8 (Q3ZCM7)
Tubulin beta-8 chain (Tubulin beta 8 class VIII)
Gene: TUBB8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003924 - GTPase activity GO:0005737 - cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 340 Hs			1 444
+	Hs
		921520 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		TBB4B_HUMAN (1-427): 0: 719: 91.10
+	Hs
		921705 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		TBB2B_HUMAN (1-430): 0: 719: 90.23
+	Hs
		921704 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		TBB6_HUMAN (1-432): 0: 715: 86.81
+	Hs
		921593 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		TBB8_HUMAN (1-427): 0: 708: 100.00
+	Hs
		1114123 WDR5B_HUMAN (71-340): 2.74e-83: 257: 25.18		TBB8_HUMAN (1-427): 0: 708: 100.00
+	Hs
		428123 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		TBB5_HUMAN (1-429): 0: 720: 89.74
+	Hs
		903115 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		TBB4B_HUMAN (1-427): 0: 719: 91.10
+	Hs
		903201 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		TBB3_HUMAN (1-442): 0: 719: 86.43
+	Hs
		381159 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		TBB4A_HUMAN (1-427): 0: 715: 90.16
+	Hs
		903481 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		TBB6_HUMAN (1-432): 0: 715: 86.81
+	Hs
		792969 LIS1_HUMAN (259-340): 1.35e-18: 87.8: 23.17		TBB4B_HUMAN (1-427): 0: 719: 91.10