HitPredict

Interactor 1: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Interactor 2: ARHGI (Q6ZSZ5)
Rho guanine nucleotide exchange factor 18 (114 kDa Rho-specific guanine nucleotide exchange factor) (p114-Rho-GEF) (p114RhoGEF) (Septin-associated RhoGEF) (SA-RhoGEF)
Gene: ARHGEF18

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14512443
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 340 Hs			1 1361
+	Hs
		921641 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		ARG28_HUMAN (52-1284): 2.53e-129: 440: 32.78
+	Hs
		921674 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		ARHG2_HUMAN (258-1241): 9.19e-103: 353: 29.62
+	Hs
		551659 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		DESP_HUMAN (378-1165): 3.52e-83: 304: 15.16
+	Hs
		1202775 WDR5B_HUMAN (71-340): 2.74e-83: 257: 25.18		ARHG1_HUMAN (249-812): 7.94e-95: 328: 25.21
+	Hs
		921728 GBB2_HUMAN (1-340): 1e-105: 314: 90.29		ECT2_HUMAN (198-907): 3.71e-73: 265: 12.31
+	Hs
		1333738 GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88		ECT2_HUMAN (198-907): 3.71e-73: 265: 12.31
+	Hs
		921052 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		ECT2_HUMAN (198-907): 3.71e-73: 265: 12.31
+	Hs
		560889 GBB3_HUMAN (1-340): 1.83e-104: 311: 83.24		ECT2_HUMAN (198-907): 3.71e-73: 265: 12.31
+	Hs
		551766 WDR5B_HUMAN (71-340): 2.74e-83: 257: 25.18		DESP_HUMAN (378-1165): 3.52e-83: 304: 15.16
+	Hs
		903416 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		ARHG2_HUMAN (258-1241): 9.19e-103: 353: 29.62
+	Hs
		224710 GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00		KALRN_HUMAN (150-997): 6.61e-56: 217: 10.58
+	Hs
		1288351 SNR40_HUMAN (130-340): 2.9e-59: 196: 24.30		ITSN2_HUMAN (434-812): 4.67e-88: 318: 23.04
+	Hs
		61736 SNR40_HUMAN (130-340): 2.9e-59: 196: 24.30		A6H8W8_HUMAN (434-812): 1.61e-87: 316: 23.04
+	Hs
		551655 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		DESP_HUMAN (378-1165): 3.52e-83: 304: 15.16
+	Hs
		297136 GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88		PKHG5_HUMAN (427-801): 3.97e-41: 167: 20.40
+	Hs
		1288311 SNR40_HUMAN (130-340): 2.9e-59: 196: 24.30		ECT2_HUMAN (198-907): 3.71e-73: 265: 12.31
+	Hs
		903526 WDR5_HUMAN (4-211): 4.16e-56: 187: 20.93		ECT2_HUMAN (198-907): 3.71e-73: 265: 12.31
+	Hs
		551854 NLE1_HUMAN (3-124): 6.68e-32: 126: 25.41		DESP_HUMAN (378-1165): 3.52e-83: 304: 15.16
+	Hs
		1254029 NLE1_HUMAN (3-124): 6.68e-32: 126: 25.41		PREX1_HUMAN (401-889): 2.18e-73: 272: 14.48
+	Hs
		551632 LIS1_HUMAN (259-340): 1.35e-18: 87.8: 23.17		DESP_HUMAN (378-1165): 3.52e-83: 304: 15.16