Interactor 1: RBX1 (P62877)
E3 ubiquitin-protein ligase RBX1 (EC 2.3.2.27) (EC 2.3.2.32) (E3 ubiquitin-protein transferase RBX1) (Protein ZYP) (RING finger protein 75) (RING-box protein 1) (Rbx1) (Regulator of cullins 1) (ROC1) [Cleaved into: E3 ubiquitin-protein ligase RBX1, N-terminally processed (E3 ubiquitin-protein transferase RBX1, N-terminally processed)]
Gene: RBX1
Interactor 2: SKP1 (P63208)
S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (p19A) (Organ of Corti protein 2) (OCP-2) (Organ of Corti protein II) (OCP-II) (RNA polymerase II elongation factor-like protein) (SIII) (Transcription elongation factor B polypeptide 1-like) (p19skp1)
Gene: SKP1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 0.60 | 0.762 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23770852, 26540345, 27705803, 29863914, 12628165, 16357137, 15452136, 29507117, 29499133, 30349055, 33692209, 33504946, 11245432, 12684064, 12504025, 12840033, 12813041 |
| Identification Methods | affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000209 - protein polyubiquitination GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol and 8 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Sp |   |
 |
|||||||||||
| + | At | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
