HitPredict

Interactor 1: GBB2 (P62879)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (G protein subunit beta-2) (Transducin beta chain 2)
Gene: GNB2

Interactor 2: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25982117, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 340 Hs			1 759
+	Hs
		1043234 GBB4_HUMAN (1-340): 3.14e-110: 326: 90.00		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		560878 GBB3_HUMAN (1-340): 2.27e-106: 316: 80.88		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		920959 GBB1_HUMAN (1-340): 1.35e-106: 316: 90.29		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1043085 WDR5B_HUMAN (89-340): 4.94e-82: 253: 25.39		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1043441 WDR5B_HUMAN (89-340): 4.94e-82: 253: 25.39		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1043114 POC1B_HUMAN (126-340): 2.42e-64: 212: 20.37		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1043157 SNR40_HUMAN (130-340): 6.93e-58: 192: 23.36		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		921555 GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		1043469 POC1B_HUMAN (126-340): 2.42e-64: 212: 20.37		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		920958 GBB1_HUMAN (1-340): 1.35e-106: 316: 90.29		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		154680 GNB5_HUMAN (129-340): 2.36e-44: 158: 20.81		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1043509 SNR40_HUMAN (130-340): 6.93e-58: 192: 23.36		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		792982 LIS1_HUMAN (258-340): 1.53e-19: 90.5: 22.89		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		903208 WDR5_HUMAN (263-340): 9.69e-19: 87.4: 26.92		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1042101 POC1B_HUMAN (126-340): 2.42e-64: 212: 20.37		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		903209 WDR5_HUMAN (263-340): 9.69e-19: 87.4: 26.92		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1042655 NLE1_HUMAN (2-124): 8.9e-29: 117: 26.77		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		903207 WDR5_HUMAN (263-340): 9.69e-19: 87.4: 26.92		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		197016 PRP4_HUMAN (51-253): 4.41e-11: 65.9: 24.88		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		903206 WDR5_HUMAN (263-340): 9.69e-19: 87.4: 26.92		CUL1_HUMAN (59-759): 0: 745: 30.55