Protein: TR112
Multifunctional methyltransferase subunit TRM112-like protein (tRNA methyltransferase 112 homolog)

Gene: TR112, TRMT112
Organism: Homo sapiens
Interactions: 80
UniProt ID: Q9UI30

Gene Ontology (top 5):
GO:0000470 - maturation of LSU-rRNA
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

224911

BUD23
18S rRNA

9

2

Small-scale

0.970

High

1414907

THUM3
tRNA

6

3

Small-scale

0.946

High

1278389

TRM11
tRNA

3

1

Small-scale

0.865

High

1385075

ALKB8
tRNA

3

1

Small-scale

0.849

High

1448741

METL5
rRNA N(6)-adenosine-methyltransferase METTL5

3

1

Small-scale

0.849

High

1460218

HEMK2
Methyltransferase HEMK2

3

2

Small-scale

0.834

High

1413523

THUM2
U6 snRNA

1

5

Small-scale

0.646

High

1232628

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.515

High

250884

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.513

High

447551

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

694054

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.513

High

1113015

CUL2
Cullin-2

1

0

High-throughput

0.513

High

1310509

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

1182871

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

1

1

High-throughput

0.501

High

339884

KLF8
Krueppel-like factor 8

1

1

High-throughput

0.500

High

1416941

KLF16
Krueppel-like factor 16

1

1

High-throughput

0.500

High

303202

RGS20
Regulator of G-protein signaling 20

1

0

High-throughput

0.493

High

894233

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.481

High

316125

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

539019

EPB41
Protein 4.1

1

1

High-throughput

0.479

High

583012

EZRI
Ezrin

1

1

High-throughput

0.479

High

1104276

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

1

High-throughput

0.479

High

1227657

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.479

High

1260636

ASXL2
Putative Polycomb group protein ASXL2

1

1

High-throughput

0.479

High

1312442

ASXL1
Polycomb group protein ASXL1

1

1

High-throughput

0.479

High

1368666

KAT6A
Histone acetyltransferase KAT6A

1

1

High-throughput

0.479

High

1420989

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.479

High

1460214

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.479

High

132368

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.458

High

243229

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

260584

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

294494

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

320126

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

607198

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

659627

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.458

High

675198

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.458

High

766924

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

785863

8ODP
Oxidized purine nucleoside triphosphate hydrolase

1

0

Small-scale

0.458

High

822903

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.458

High

831605

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

879594

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

905261

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

920340

PLK1
Serine/threonine-protein kinase PLK1

1

0

High-throughput

0.458

High

947307

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.458

High

965312

WDR5
WD repeat-containing protein 5

1

0

High-throughput

0.458

High

971253

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

975301

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.458

High

980501

H4
Histone H4

1

0

High-throughput

0.458

High

985942

RL11
Large ribosomal subunit protein uL5

1

0

Small-scale

0.458

High

1122580

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

0

High-throughput

0.458

High

1138148

TNIP1
TNFAIP3-interacting protein 1

1

0

High-throughput

0.458

High

1138732

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1178452

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1255995

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1357600

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.458

High

1367527

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

1397534

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1434171

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1435418

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1450912

RNF12
E3 ubiquitin-protein ligase RLIM

1

0

High-throughput

0.458

High

1451310

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

1459217

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1460213

TNIK
TRAF2 and NCK-interacting protein kinase

1

0

High-throughput

0.458

High

1460216

AAKB1
5'-AMP-activated protein kinase subunit beta-1

1

0

High-throughput

0.458

High

1460217

TRAF6
TNF receptor-associated factor 6

1

0

High-throughput

0.458

High

1460219

MAFB
Transcription factor MafB

1

0

High-throughput

0.458

High

1119025

BYST
Bystin

1

1

High-throughput

0.445

High

1209770

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

1370151

RENT1
Regulator of nonsense transcripts 1

1

0

High-throughput

0.438

High

1034540

TAGL
Transgelin

1

0

High-throughput

0.426

High

1130506

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.426

High

1411749

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.426

High

1420753

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

1451892

MED29
Mediator of RNA polymerase II transcription subunit 29

1

0

High-throughput

0.426

High

1449407

SLX9
Ribosome biogenesis protein SLX9 homolog

2

0

High-throughput

0.313

High

380180

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.249

Low

418502

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.249

Low

914223

EFNA3
Ephrin-A3

1

0

High-throughput

0.249

Low

1348242

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

1460215

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025