HitPredict

Interactor 1: PROF1 (P62962)
Profilin-1 (Profilin I)
Gene: Pfn1

Interactor 2: ENAH (Q03173)
Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1)
Gene: ENAH

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	8861907
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001843 - neural tube closure GO:0003779 - actin binding GO:0005829 - cytosol GO:0030036 - actin cytoskeleton organization
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 140 Mm			1 802
+	Mm
		975407 PROF2_MOUSE (1-140): 2.21e-73: 217: 62.86		ENAH_MOUSE (1-802): 1.66e-73: 257: 100.00
+	Hs
		430372 PROF1_HUMAN (1-140): 8.78e-78: 228: 95.71		EVL_HUMAN (1-372): 6.55e-32: 131: 27.61
+	Hs
		715013 PROF2_HUMAN (1-140): 2.66e-73: 216: 62.86		EVL_HUMAN (1-372): 6.55e-32: 131: 27.61
+	Hs
		430098 PROF1_HUMAN (1-140): 8.78e-78: 228: 95.71		VASP_HUMAN (1-311): 7.93e-27: 115: 29.39
+	Hs
		714941 PROF2_HUMAN (1-140): 2.66e-73: 216: 62.86		VASP_HUMAN (1-311): 7.93e-27: 115: 29.39
+	Hs
		430264 PROF1_HUMAN (1-140): 8.78e-78: 228: 95.71		ENAH_HUMAN (497-802): 2.03e-11: 69.6: 79.51
+	Mm
		923936 PROF1_MOUSE (1-140): 6.53e-78: 228: 100.00		PCLO_MOUSE (89-796): 6.09e-10: 65.3: 9.55
+	Mm
		936836 PROF2_MOUSE (1-140): 2.21e-73: 217: 62.86		VASP_MOUSE (574-801): 2.66e-12: 71.4: 32.02
+	Hs
		714977 PROF2_HUMAN (1-140): 2.66e-73: 216: 62.86		ENAH_HUMAN (497-802): 2.03e-11: 69.6: 79.51
+	Mm
		1337493 PROF2_MOUSE (1-140): 2.21e-73: 217: 62.86		PCLO_MOUSE (89-796): 6.09e-10: 65.3: 9.55