HitPredict

Interactor 1: RL40 (P62987)
Ubiquitin-ribosomal protein eL40 fusion protein (CEP52) (Ubiquitin A-52 residue ribosomal protein fusion product 1) [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40 (60S ribosomal protein L40)]
Gene: UBA52

Interactor 2: H2A3 (Q7L7L0)
Histone H2A type 3 (H2A-clustered histone 25)
Gene: H2AC25

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 128 Hs			1 130
+	Hs
		391644 RL40_HUMAN (1-128): 1.05e-56: 174: 100.00		H2A1B_HUMAN (1-130): 7.3e-68: 202: 99.23
+	Hs
		470332 RL40_HUMAN (1-128): 1.05e-56: 174: 100.00		H2A1_HUMAN (1-130): 5.87e-68: 202: 97.69
+	Hs
		924322 RL40_HUMAN (1-128): 1.05e-56: 174: 100.00		H2A2A_HUMAN (1-130): 4.18e-68: 202: 97.69
+	Hs
		924374 RL40_HUMAN (1-128): 1.05e-56: 174: 100.00		H2A1C_HUMAN (1-130): 4.66e-68: 202: 99.23
+	Hs
		924397 RL40_HUMAN (1-128): 1.05e-56: 174: 100.00		H2A1J_HUMAN (1-128): 2.34e-67: 201: 96.88
+	Hs
		924387 RL40_HUMAN (1-128): 1.05e-56: 174: 100.00		H2A1H_HUMAN (1-128): 3.59e-67: 200: 97.66
+	Hs
		555404 RL40_HUMAN (1-128): 1.05e-56: 174: 100.00		H2AX_HUMAN (1-130): 5.7e-64: 192: 88.81
+	Sc
		392251 RL40A_YEAST (1-128): 1.32e-53: 166: 89.84		H2A2_YEAST (16-128): 1.62e-59: 181: 80.53
+	Hs
		391643 RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70		H2A1B_HUMAN (1-130): 7.3e-68: 202: 99.23
+	Hs
		470331 RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70		H2A1_HUMAN (1-130): 5.87e-68: 202: 97.69
+	Hs
		924034 RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70		H2A2A_HUMAN (1-130): 4.18e-68: 202: 97.69
+	Hs
		924049 RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70		H2A3_HUMAN (1-130): 4.87e-68: 202: 100.00
+	Hs
		555403 RS27A_HUMAN (1-77): 2.11e-38: 128: 98.70		H2AX_HUMAN (1-130): 5.7e-64: 192: 88.81
+	Hs
		474911 UBB_HUMAN (1-76): 1.52e-33: 118: 100.00		H2AX_HUMAN (1-130): 5.7e-64: 192: 88.81
+	At
		1092092 UBQ3_ARATH (1-78): 1.98e-32: 117: 93.59		H2A6_ARATH (1-128): 9.07e-60: 181: 71.32
+	Dm
		950447 R9PY16_DROME (1-68): 2.05e-27: 104: 91.18		H2A_DROME (17-125): 5.76e-60: 182: 89.91