HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: BICRA (Q9NZM4)
BRD4-interacting chromatin-remodeling complex-associated protein (Glioma tumor suppressor candidate region gene 1 protein)
Gene: BICRA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 217 Hs			1 1560
+	Hs
		557809 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		BICRA_HUMAN (1-1560): 1.85e-111: 390: 100.00
+	Hs
		554292 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		MUC1_HUMAN (568-1550): 6.44e-50: 196: 13.82
+	Hs
		411582 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		MUC1_HUMAN (568-1550): 6.44e-50: 196: 13.82
+	Hs
		924760 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		PRG4_HUMAN (67-728): 1.32e-15: 85.1: 11.38
+	Hs
		517796 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		NFH_HUMAN (515-1037): 2.23e-14: 80.7: 13.12
+	Hs
		924808 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		MINT_HUMAN (202-989): 5.58e-14: 79.9: 15.09
+	Hs
		203218 GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00		SYNJ1_HUMAN (296-688): 7.39e-10: 66.4: 15.07
+	Hs
		337335 ABL1_HUMAN (4-139): 4.39e-22: 95.5: 35.46		MUC1_HUMAN (568-1550): 6.44e-50: 196: 13.82
+	Hs
		433560 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		MUC1_HUMAN (568-1550): 6.44e-50: 196: 13.82
+	Hs
		522749 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		MUC1_HUMAN (568-1550): 6.44e-50: 196: 13.82
+	Hs
		203198 LCK_HUMAN (3-202): 3.69e-37: 137: 28.91		SYNJ1_HUMAN (296-688): 7.39e-10: 66.4: 15.07
+	Hs
		557777 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		MINT_HUMAN (202-989): 5.58e-14: 79.9: 15.09
+	Hs
		782839 CSK_HUMAN (2-139): 3.92e-24: 100: 36.24		NCOR2_HUMAN (339-1556): 7.75e-13: 76: 9.55
+	Hs
		434084 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		SRRM2_HUMAN (28-1524): 1.56e-19: 98.3: 8.01
+	Hs
		203208 NCK1_HUMAN (5-145): 9.45e-23: 96.3: 33.14		SYNJ1_HUMAN (296-688): 7.39e-10: 66.4: 15.07
+	Hs
		297808 LYN_HUMAN (129-215): 1.44e-11: 65: 22.47		K0754_HUMAN (1199-1548): 1.08e-15: 85.5: 12.39
+	Hs
		257713 ITSN2_HUMAN (2-61): 5.91e-15: 75: 36.67		ANR17_HUMAN (636-1141): 1.65e-11: 71.8: 17.00
+	Hs
		412362 FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58		MAGE1_HUMAN (384-805): 3.12e-09: 64.1: 19.72
+	Hs
		203228 ITSN1_HUMAN (137-216): 1.36e-12: 68.1: 25.00		SYNJ1_HUMAN (296-688): 7.39e-10: 66.4: 15.07
+	Hs
		64077 SRC_HUMAN (161-215): 3.76e-11: 63.8: 31.58		L37A2_HUMAN (665-1118): 2.19e-09: 64.9: 16.83