Protein: YPK1
Serine/threonine-protein kinase YPK1 (EC 2.7.11.1) (Sphingosine-like immunosuppressant resistant protein 2) (Yeast protein kinase 1)

Gene: YPK1
Organism: Saccharomyces cerevisiae S288C
Interactions: 105
UniProt ID: P12688

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

520632

FPK1
Flippase kinase 1

4

16

Small-scale

0.903

High

520572

HSC82
ATP-dependent molecular chaperone HSC82

3

20

High-throughput

0.817

High

520642

PKH1
Serine/threonine-protein kinase PKH1

2

17

Small-scale

0.778

High

520592

TOR2
Serine/threonine-protein kinase TOR2

4

20

Small-scale

0.694

High

520577

DBF2
Cell cycle protein kinase DBF2

1

17

High-throughput

0.691

High

520589

DBF20
Serine/threonine-protein kinase DBF20

1

17

High-throughput

0.691

High

520574

YPK2
Serine/threonine-protein kinase YPK2/YKR2

1

16

High-throughput

0.665

High

520649

YSP2
Membrane-anchored lipid-binding protein YSP2

3

5

Small-scale

0.655

High

439614

SPS1
Sporulation-specific protein 1

1

18

High-throughput

0.647

High

520578

RAD53
Serine/threonine-protein kinase RAD53

1

15

High-throughput

0.647

High

520616

SLM1
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1

3

0

Small-scale

0.629

High

365679

HSP82
ATP-dependent molecular chaperone HSP82

1

20

High-throughput

0.618

High

490158

HSP71
Heat shock protein SSA1

3

13

High-throughput

0.611

High

520579

FPS1
Glycerol uptake/efflux facilitator protein

2

1

Small-scale

0.602

High

520630

ORM1
Protein ORM1

2

1

Small-scale

0.602

High

520647

ORM2
Protein ORM2

2

1

Small-scale

0.602

High

520588

HS104
Heat shock protein 104

2

2

High-throughput

0.584

High

520623

JSN1
Protein JSN1

1

1

Small-scale

0.579

High

520656

PUF2
mRNA-binding protein PUF2

1

1

Small-scale

0.579

High

520635

GPD1
Glycerol-3-phosphate dehydrogenase [NAD(+)] 1

2

0

Small-scale

0.577

High

520638

ROD1
Protein ROD1

2

0

Small-scale

0.577

High

520639

MUK1
Protein MUK1

2

0

Small-scale

0.577

High

520583

MAS5
Mitochondrial protein import protein MAS5

1

6

High-throughput

0.575

High

520609

CAJ1
Protein CAJ1

1

9

High-throughput

0.575

High

520620

JJJ2
J protein JJJ2

1

10

High-throughput

0.575

High

477838

HSP77
Import motor subunit, mitochondrial

2

19

High-throughput

0.571

High

520584

RS5
Small ribosomal subunit protein uS7

1

3

Small-scale

0.561

High

510069

SSB1
Ribosome-associated molecular chaperone SSB1

2

13

High-throughput

0.552

High

520575

HSP60
Heat shock protein 60, mitochondrial

2

14

High-throughput

0.552

High

520614

SSB2
Ribosome-associated molecular chaperone SSB2

2

13

High-throughput

0.552

High

520587

XPO1
Exportin-1

1

6

High-throughput

0.536

High

520604

IF5
Eukaryotic translation initiation factor 5

1

4

High-throughput

0.536

High

520613

TSC11
Target of rapamycin complex 2 subunit TSC11

1

8

High-throughput

0.536

High

520615

MOB1
DBF2 kinase activator protein MOB1

1

2

High-throughput

0.536

High

520650

AVO1
Target of rapamycin complex 2 subunit AVO1

1

2

High-throughput

0.536

High

520573

TEC1
Ty transcription activator TEC1

1

1

High-throughput

0.515

High

520591

FIMB
Fimbrin

1

3

High-throughput

0.515

High

520627

INP52
Polyphosphatidylinositol phosphatase INP52

1

1

High-throughput

0.515

High

520644

GIS4
Protein GIS4

1

0

High-throughput

0.513

High

421560

FAS1
Fatty acid synthase subunit beta

1

3

High-throughput

0.501

High

520595

TOR1
Serine/threonine-protein kinase TOR1

1

20

Small-scale

0.501

High

520601

SMP1
Transcription factor SMP1

1

3

Small-scale

0.501

High

520607

LAM4
Membrane-anchored lipid-binding protein LAM4

1

5

Small-scale

0.501

High

520608

YHP7
Uncharacterized protein YHR097C

1

1

Small-scale

0.501

High

520625

CCH1
Calcium-channel protein CCH1

1

1

Small-scale

0.501

High

520612

RPN3
26S proteasome regulatory subunit RPN3

1

2

High-throughput

0.494

High

520637

ACAC
Acetyl-CoA carboxylase

1

9

Small-scale

0.481

High

520581

GLRX1
Glutaredoxin-1

1

0

High-throughput

0.480

High

520640

ATG21
Autophagy-related protein 21

1

0

Small-scale

0.480

High

405384

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.479

High

406721

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

470813

RS22A
Small ribosomal subunit protein uS8A

1

2

High-throughput

0.479

High

471978

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.479

High

479878

RS6A
Small ribosomal subunit protein eS6A

1

6

High-throughput

0.479

High

485621

IF4A
ATP-dependent RNA helicase eIF4A

1

10

High-throughput

0.479

High

520576

DBP5
ATP-dependent RNA helicase DBP5

1

11

High-throughput

0.479

High

520582

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.479

High

520586

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

520593

SMY2
Protein SMY2

1

2

High-throughput

0.479

High

520594

RS3A1
Small ribosomal subunit protein eS1A

1

3

High-throughput

0.479

High

520597

SPT10
Protein SPT10

1

1

High-throughput

0.479

High

520600

GBLP
Small ribosomal subunit protein RACK1

1

14

Small-scale

0.479

High

520618

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

5

High-throughput

0.479

High

520622

MOG1
Nuclear import protein MOG1

1

1

High-throughput

0.479

High

520626

UBC9
SUMO-conjugating enzyme UBC9

1

2

High-throughput

0.479

High

520628

CDH1
APC/C activator protein CDH1

1

12

Small-scale

0.479

High

520633

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

1

High-throughput

0.479

High

520634

H3
Histone H3

1

12

High-throughput

0.479

High

520641

ESP1
Separin

1

1

High-throughput

0.479

High

520643

SIZ1
E3 SUMO-protein ligase SIZ1

1

4

High-throughput

0.479

High

520646

SYRC
Arginine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

520654

RIO1
Serine/threonine-protein kinase RIO1

1

2

High-throughput

0.479

High

520655

SIZ2
E3 SUMO-protein ligase SIZ2

1

4

High-throughput

0.479

High

520659

AHA1
Hsp90 co-chaperone AHA1

1

3

High-throughput

0.479

High

520660

CMR1
DNA damage-binding protein CMR1

1

9

High-throughput

0.479

High

520648

CORO
Coronin-like protein

1

5

High-throughput

0.470

High

520653

LEU9
2-isopropylmalate synthase 2, mitochondrial

1

2

High-throughput

0.470

High

520598

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

520605

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

520610

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

520645

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

520652

MCA1
Metacaspase-1

1

0

High-throughput

0.458

High

520585

LAC1
Ceramide synthase LAC1

1

4

Small-scale

0.457

High

520606

LAG1
Ceramide synthase LAG1

1

4

Small-scale

0.457

High

520657

HER1
HMG2-induced ER-remodeling protein 1

1

1

Small-scale

0.457

High

520596

GCS1
ADP-ribosylation factor GTPase-activating protein GCS1

1

11

High-throughput

0.457

High

367669

EF1A
Elongation factor 1-alpha

1

5

High-throughput

0.445

High

424307

PYR1
Multifunctional protein URA2

1

4

High-throughput

0.445

High

493046

HSP72
Heat shock protein SSA2

1

13

High-throughput

0.445

High

520590

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

520603

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

7

High-throughput

0.445

High

520571

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.437

High

520636

NUM1
Nuclear migration protein NUM1

1

16

High-throughput

0.437

High

520580

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.426

High

520619

RRP41
Exosome complex component SKI6

1

0

High-throughput

0.426

High

520624

MTR3
Exosome complex component MTR3

1

0

High-throughput

0.426

High

520651

RRP40
Exosome complex component RRP40

1

0

High-throughput

0.426

High

520658

HSP42
Heat shock protein 42

1

2

High-throughput

0.407

High

520599

GPT2
Glycerol-3-phosphate O-acyltransferase 2

1

0

Small-scale

0.261

Low

520617

CDC1
Cell division control protein 1

1

0

Small-scale

0.261

Low

520621

DS1P1
Dihydrosphingosine 1-phosphate phosphatase LCB3

1

0

Small-scale

0.261

Low

520629

PEX31
Peroxisomal membrane protein PEX31

1

0

Small-scale

0.261

Low

520631

YN87
Uncharacterized protein YNR014W

1

0

Small-scale

0.261

Low

520602

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

520611

ISC1
Inositol phosphosphingolipids phospholipase C

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024