HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: SWAHC (Q53LP3)
Ankyrin repeat domain-containing protein SOWAHC (Ankyrin repeat domain-containing protein 57) (Protein sosondowah homolog C)
Gene: SOWAHC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 525
+	Hs
		892407 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		SWAHC_HUMAN (1-525): 1.01e-117: 358: 100.00
+	Hs
		951048 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		SWAHC_HUMAN (1-525): 1.01e-117: 358: 100.00
+	Hs
		894087 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		SWAHC_HUMAN (1-525): 1.01e-117: 358: 100.00
+	Hs
		925238 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		ANK3_HUMAN (272-522): 9.35e-39: 153: 16.19
+	Hs
		925204 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		ANK2_HUMAN (260-522): 2.09e-37: 150: 14.77
+	Hs
		950953 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		ANK3_HUMAN (272-522): 9.35e-39: 153: 16.19
+	Hs
		893947 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		ANK3_HUMAN (272-522): 9.35e-39: 153: 16.19
+	Hs
		925723 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Hs
		564734 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Mm
		892714 RAC3_MOUSE (1-191): 2.72e-79: 236: 93.19		ANS1B_MOUSE (266-509): 8.36e-33: 135: 15.36
+	Hs
		545696 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Hs
		1330985 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Hs
		892676 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Hs
		951454 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Hs
		894580 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		KDIS_HUMAN (1-344): 1.09e-27: 120: 11.34
+	Hs
		925249 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		ILK_HUMAN (284-382): 7.22e-16: 81.9: 29.29
+	Mm
		82719 RAC3_MOUSE (1-191): 2.72e-79: 236: 93.19		CTTB2_MOUSE (82-366): 1.81e-20: 97.7: 11.25
+	Hs
		564510 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		ILK_HUMAN (284-382): 7.22e-16: 81.9: 29.29
+	Hs
		1033553 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		ILK_HUMAN (284-382): 7.22e-16: 81.9: 29.29
+	Hs
		893969 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		ILK_HUMAN (284-382): 7.22e-16: 81.9: 29.29