HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: JPH1 (Q9HDC5)
Junctophilin-1 (JP-1) (Junctophilin type 1)
Gene: JPH1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 661
+	Hs
		564696 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		JPH1_HUMAN (1-661): 1.8e-151: 455: 100.00
+	Hs
		545633 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		JPH1_HUMAN (1-661): 1.8e-151: 455: 100.00
+	Hs
		1330929 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		JPH1_HUMAN (1-661): 1.8e-151: 455: 100.00
+	Hs
		892611 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		JPH1_HUMAN (1-661): 1.8e-151: 455: 100.00
+	Hs
		951365 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		JPH1_HUMAN (1-661): 1.8e-151: 455: 100.00
+	Hs
		894465 CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31		JPH1_HUMAN (1-661): 1.8e-151: 455: 100.00
+	Hs
		900935 RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98		JPH1_HUMAN (1-661): 1.8e-151: 455: 100.00
+	Hs
		564614 RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67		MORN4_HUMAN (98-238): 7.98e-26: 105: 21.83
+	Hs
		297823 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		K0754_HUMAN (147-515): 1.05e-13: 77.1: 8.62
+	Hs
		925532 RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00		ALS2_HUMAN (104-332): 1.48e-13: 76.7: 15.00
+	Hs
		297812 RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19		K0754_HUMAN (147-515): 1.05e-13: 77.1: 8.62
+	Hs
		951193 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		RSPH1_HUMAN (107-375): 2.1e-16: 82.5: 11.68
+	Hs
		297840 RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64		K0754_HUMAN (147-515): 1.05e-13: 77.1: 8.62
+	Ce
		136793 RAC1_CAEEL (1-192): 2.2e-83: 246: 82.81		UNC89_CAEEL (384-635): 3.2e-11: 69.2: 11.79
+	Hs
		297819 RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19		K0754_HUMAN (147-515): 1.05e-13: 77.1: 8.62
+	Hs
		297827 RHOG_HUMAN (1-192): 3.1e-79: 236: 71.35		K0754_HUMAN (147-515): 1.05e-13: 77.1: 8.62
+	Hs
		297820 RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98		K0754_HUMAN (147-515): 1.05e-13: 77.1: 8.62
+	Ce
		104464 G5EBV3_CAEEL (2-192): 6.22e-78: 232: 65.45		UNC89_CAEEL (384-635): 3.2e-11: 69.2: 11.79
+	Ce
		136794 CDC42_CAEEL (1-192): 5.89e-76: 227: 69.27		UNC89_CAEEL (384-635): 3.2e-11: 69.2: 11.79
+	Ce
		136800 RHO1_CAEEL (5-192): 4.91e-75: 225: 59.04		UNC89_CAEEL (384-635): 3.2e-11: 69.2: 11.79