Interactor 1: AP2B1 (P63010)
AP-2 complex subunit beta (AP105B) (Adaptor protein complex AP-2 subunit beta) (Adaptor-related protein complex 2 subunit beta) (Beta-2-adaptin) (Beta-adaptin) (Clathrin assembly protein complex 2 beta large chain) (Plasma membrane adaptor HA2/AP2 adaptin beta subunit)
Gene: AP2B1

Interactor 2: AP1B1 (Q10567)
AP-1 complex subunit beta-1 (Adaptor protein complex AP-1 subunit beta-1) (Adaptor-related protein complex 1 subunit beta-1) (Beta-1-adaptin) (Beta-adaptin 1) (Clathrin assembly protein complex 1 beta large chain) (Golgi adaptor HA1/AP1 adaptin beta subunit)
Gene: AP1B1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 33961781, 36652389
Identification Methods affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Adaptin_N~Adaptin_N, Alpha_adaptinC2~Alpha_adaptinC2, Alpha_adaptinC2~B2-adapt-app_C
Common GO terms GO:0001822 - kidney development
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
GO:0016192 - vesicle-mediated transport
GO:0030276 - clathrin binding
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 937
Hs

1 949
+ Hs
+ Mm
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+ Hs
+ Hs
+ Dm
+ At
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+ At

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Last updated: 15 Jul 2024