Interactor 1: VAMP2 (P63027)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Interactor 2: STX3 (Q13277)
Syntaxin-3
Gene: STX3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.923

The method score is based on:

Property Details
Experiments 29360461, 26186194, 28514442, 12828989, 33961781
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains SNARE~Synaptobrevin, Synaptobrevin~Syntaxin
Common GO terms GO:0000149 - SNARE binding
GO:0005484 - SNAP receptor activity
GO:0005886 - plasma membrane
GO:0008021 - synaptic vesicle
GO:0031201 - SNARE complex
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 116
Hs

1 289
+ Rn
+ Dm
+ Dm
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ At
+ Dm
+ Dm
+ Dm
+ At
+ Dm
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024