HitPredict

Interactor 1: VAMP2 (P63027)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Interactor 2: RND1 (Q92730)
Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1)
Gene: RND1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 116 Hs			1 232
+	Hs
		850550 VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		850544 VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31		RND2_HUMAN (12-232): 9.62e-80: 240: 53.15
+	Hs
		850556 VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31		RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42
+	Hs
		850548 VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31		RAC3_HUMAN (11-188): 5.54e-77: 232: 39.89
+	Hs
		850554 VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31		RB11A_HUMAN (1-231): 1.91e-76: 231: 18.88
+	Hs
		545275 VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31		RAC2_HUMAN (11-201): 1.34e-76: 230: 38.22
+	Hs
		850552 VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Hs
		850558 VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31		RHOG_HUMAN (11-198): 1.56e-76: 230: 37.77
+	Mm
		892719 VAMP2_MOUSE (25-116): 9.9e-26: 94.7: 100.00		CDC42_MOUSE (11-197): 1.18e-80: 241: 37.43
+	Hs
		893880 VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00		CDC42_HUMAN (11-197): 1.18e-80: 241: 37.43
+	Hs
		925171 VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00		RAC1_HUMAN (11-200): 6.76e-80: 239: 38.42
+	Hs
		261649 VAMP4_HUMAN (18-99): 1.04e-26: 97.8: 35.37		RB11A_HUMAN (1-231): 1.91e-76: 231: 18.88
+	Hs
		913996 VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00		RB11A_HUMAN (1-231): 1.91e-76: 231: 18.88
+	Hs
		545311 VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00		RAC2_HUMAN (11-201): 1.34e-76: 230: 38.22
+	Hs
		900359 VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00		RHOA_HUMAN (15-198): 2.7e-76: 230: 42.94
+	Hs
		436215 VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31		RHOC_HUMAN (13-184): 4.59e-50: 163: 46.51
+	Hs
		850555 VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31		RHOB_HUMAN (13-190): 2.91e-49: 161: 44.94
+	Hs
		120358 VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31		RHOD_HUMAN (6-189): 1.79e-48: 160: 40.76
+	Hs
		436247 VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00		RHOC_HUMAN (13-184): 4.59e-50: 163: 46.51
+	Hs
		915589 VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00		RHOB_HUMAN (13-190): 2.91e-49: 161: 44.94