HitPredict

Interactor 1: 1433Z (P63101)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1) (SEZ-2)
Gene: Ywhaz

Interactor 2: RIMS3 (Q80U57)
Regulating synaptic membrane exocytosis protein 3 (Nim3) (RIM3 gamma) (Rab-3-interacting molecule 3) (RIM 3)
Gene: RIMS3

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16959763
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0044325 - transmembrane transporter binding GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Mm			1 307
+	Mm
		910280 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		RIMS3_MOUSE (1-307): 1.3e-82: 253: 100.00
+	Hs
		135776 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		P3C2B_HUMAN (132-275): 1.79e-48: 175: 33.11
+	Hs
		135774 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		P3C2B_HUMAN (132-275): 1.79e-48: 175: 33.11
+	Hs
		135766 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		P3C2B_HUMAN (132-275): 1.79e-48: 175: 33.11
+	Hs
		566348 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		KPCA_HUMAN (149-280): 2.85e-45: 164: 26.12
+	Hs
		135769 1433B_HUMAN (1-242): 9.01e-140: 393: 88.02		P3C2B_HUMAN (132-275): 1.79e-48: 175: 33.11
+	Hs
		397155 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		KPCG_HUMAN (149-280): 8.19e-45: 163: 30.37
+	Hs
		566293 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		KPCA_HUMAN (149-280): 2.85e-45: 164: 26.12
+	Hs
		128838 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		P3C2A_HUMAN (154-281): 1.53e-25: 108: 25.76
+	Hs
		128836 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		P3C2A_HUMAN (154-281): 1.53e-25: 108: 25.76
+	Rn
		926903 1433Z_RAT (1-245): 3.48e-145: 407: 100.00		RIMS1_RAT (69-285): 2.85e-22: 99.2: 19.56
+	Hs
		128810 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		P3C2A_HUMAN (154-281): 1.53e-25: 108: 25.76
+	Hs
		927239 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		RIMS1_HUMAN (69-285): 8.44e-22: 97.7: 19.11
+	Rn
		910361 1433E_RAT (2-241): 9.9e-144: 403: 68.18		RIMS1_RAT (69-285): 2.85e-22: 99.2: 19.56
+	Dm
		664613 1433Z_DROME (1-245): 3.35e-143: 402: 81.63		Q7K3H0_DROME (156-275): 1.05e-22: 100: 30.08
+	Mm
		910341 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		RIMS2_MOUSE (104-276): 4.07e-22: 98.8: 19.89
+	Hs
		128813 1433B_HUMAN (1-242): 9.01e-140: 393: 88.02		P3C2A_HUMAN (154-281): 1.53e-25: 108: 25.76
+	Hs
		909754 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		RIMS1_HUMAN (69-285): 8.44e-22: 97.7: 19.11
+	Hs
		647061 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		RIMS1_HUMAN (69-285): 8.44e-22: 97.7: 19.11
+	Hs
		48275 1433B_HUMAN (1-242): 9.01e-140: 393: 88.02		ESYT2_HUMAN (167-300): 1.68e-13: 73: 19.86