HitPredict

Interactor 1: 1433Z (P63101)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1) (SEZ-2)
Gene: Ywhaz

Interactor 2: HOME1 (Q9Z2Y3)
Homer protein homolog 1 (Homer-1) (VASP/Ena-related gene up-regulated during seizure and LTP 1) (Vesl-1)
Gene: Homer1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	16959763, 28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0044325 - transmembrane transporter binding GO:0044877 - protein-containing complex binding GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Mm			1 366
+	Mm
		910353 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		HOME1_MOUSE (1-366): 1.14e-85: 265: 100.00
+	Hs
		927261 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		HOME1_HUMAN (1-366): 4.29e-83: 258: 94.81
+	Hs
		683519 1433B_HUMAN (1-242): 9.01e-140: 393: 88.02		HOME1_HUMAN (1-366): 4.29e-83: 258: 94.81
+	Hs
		927145 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		MRCKA_HUMAN (1-348): 1.31e-70: 241: 17.13
+	Hs
		909658 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		MRCKA_HUMAN (1-348): 1.31e-70: 241: 17.13
+	Hs
		646981 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		MRCKA_HUMAN (1-348): 1.31e-70: 241: 17.13
+	Hs
		683425 1433B_HUMAN (1-242): 9.01e-140: 393: 88.02		MRCKA_HUMAN (1-348): 1.31e-70: 241: 17.13
+	Mm
		926869 1433Z_MOUSE (1-245): 3.48e-145: 407: 100.00		HOME3_MOUSE (3-366): 2.41e-69: 223: 46.98
+	Mm
		1321773 1433B_MOUSE (1-242): 1.98e-128: 364: 86.78		HOME1_MOUSE (1-366): 1.14e-85: 265: 100.00
+	Mm
		910327 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		HOME3_MOUSE (3-366): 2.41e-69: 223: 46.98
+	Hs
		927164 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		MRCKG_HUMAN (1-357): 8.45e-56: 199: 17.87
+	Hs
		909524 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		ROCK1_HUMAN (1-364): 9.82e-39: 149: 16.58
+	Mm
		926781 1433Z_MOUSE (1-245): 3.48e-145: 407: 100.00		ENAH_MOUSE (1-182): 5.83e-33: 132: 22.40
+	Hs
		840453 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		VASP_HUMAN (1-359): 1.49e-34: 132: 15.51
+	Hs
		840451 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		VASP_HUMAN (1-359): 1.49e-34: 132: 15.51
+	Hs
		646733 1433T_HUMAN (1-245): 2.6e-140: 395: 80.00		VASP_HUMAN (1-359): 1.49e-34: 132: 15.51
+	Mm
		926774 1433Z_MOUSE (1-245): 3.48e-145: 407: 100.00		EVL_MOUSE (1-167): 1.76e-23: 102: 20.35
+	Hs
		551660 1433Z_HUMAN (1-245): 1.67e-144: 405: 99.59		DESP_HUMAN (72-362): 5.09e-09: 60: 12.42
+	Mm
		93548 1433E_MOUSE (2-241): 9.9e-144: 403: 68.18		DESP_MOUSE (72-361): 3.8e-09: 60.4: 12.62
+	Hs
		551656 1433G_HUMAN (1-240): 8.4e-109: 315: 74.59		DESP_HUMAN (72-362): 5.09e-09: 60: 12.42