HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: TISB (Q07352)
mRNA decay activator protein ZFP36L1 (Butyrate response factor 1) (EGF-response factor 1) (ERF-1) (TPA-induced sequence 11b) (Zinc finger protein 36, C3H1 type-like 1) (ZFP36-like 1)
Gene: ZFP36L1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	35271311, 15538381
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070371 - ERK1 and ERK2 cascade
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 338
+	Hs
		909474 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		TISB_HUMAN (1-338): 1.64e-99: 298: 100.00
+	Hs
		646828 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		TISB_HUMAN (1-338): 1.64e-99: 298: 100.00
+	Hs
		683291 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		TISB_HUMAN (1-338): 1.64e-99: 298: 100.00
+	Hs
		904481 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		TISB_HUMAN (1-338): 1.64e-99: 298: 100.00
+	Hs
		981948 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		TISB_HUMAN (1-338): 1.64e-99: 298: 100.00
+	Hs
		683988 1433S_HUMAN (1-237): 8.27e-104: 302: 71.97		TISB_HUMAN (1-338): 1.64e-99: 298: 100.00
+	Hs
		815222 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		TISD_HUMAN (23-223): 4.24e-38: 143: 46.88
+	Hs
		815212 1433E_HUMAN (2-241): 9.9e-144: 403: 68.18		TISD_HUMAN (23-223): 4.24e-38: 143: 46.88
+	Hs
		646718 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		TISD_HUMAN (23-223): 4.24e-38: 143: 46.88
+	Hs
		683197 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		TISD_HUMAN (23-223): 4.24e-38: 143: 46.88
+	Hs
		644227 1433T_HUMAN (1-245): 2.6e-140: 395: 79.59		TTP_HUMAN (95-337): 1.21e-33: 128: 34.90
+	Hs
		644231 1433B_HUMAN (1-242): 9.01e-140: 393: 87.60		TTP_HUMAN (95-337): 1.21e-33: 128: 34.90
+	Mm
		612137 1433B_MOUSE (1-242): 3.77e-128: 364: 87.19		TTP_MOUSE (95-337): 1.96e-36: 135: 34.00
+	Hs
		815209 1433G_HUMAN (1-240): 2.37e-108: 314: 74.59		TISD_HUMAN (23-223): 4.24e-38: 143: 46.88
+	Hs
		815235 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		TISD_HUMAN (23-223): 4.24e-38: 143: 46.88
+	Hs
		683898 1433S_HUMAN (1-237): 8.27e-104: 302: 71.97		TISD_HUMAN (23-223): 4.24e-38: 143: 46.88
+	Hs
		644242 1433F_HUMAN (2-240): 1.26e-107: 312: 74.49		TTP_HUMAN (95-337): 1.21e-33: 128: 34.90