HitPredict

Interactor 1: E9PQQ4 (E9PQQ4)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8)
Gene: HSPA8

Interactor 2: DNJB4 (Q9UDY4)
DnaJ homolog subfamily B member 4 (Heat shock 40 kDa protein 1 homolog) (HSP40 homolog) (Heat shock protein 40 homolog) (Human liver DnaJ-like protein)
Gene: DNAJB4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	DnaJ~HSP70
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 171 Hs			1 337
+	Hs
		504901 HSP7C_HUMAN (1-171): 4.49e-104: 313: 100.00		DNJB4_HUMAN (1-337): 9.06e-140: 400: 100.00
+	Hs
		483809 HS71B_HUMAN (1-171): 5.2e-102: 307: 87.72		DNJB4_HUMAN (1-337): 9.06e-140: 400: 100.00
+	Hs
		714088 HS71L_HUMAN (2-171): 5.25e-101: 305: 84.71		DNJB4_HUMAN (1-337): 9.06e-140: 400: 100.00
+	Hs
		279272 HSP7C_HUMAN (1-171): 4.49e-104: 313: 100.00		DNJB5_HUMAN (1-337): 1.41e-131: 380: 60.92
+	Hs
		279280 HS71L_HUMAN (2-171): 5.25e-101: 305: 84.71		DNJB5_HUMAN (1-337): 1.41e-131: 380: 60.92
+	Hs
		503463 HSP7C_HUMAN (1-171): 4.49e-104: 313: 100.00		DNJB1_HUMAN (1-335): 7.26e-127: 368: 64.60
+	Hs
		92694 E9PQQ4_HUMAN (1-171): 1.1e-108: 308: 100.00		DNJB1_HUMAN (1-335): 7.26e-127: 368: 64.60
+	Hs
		483773 HS71B_HUMAN (1-171): 5.2e-102: 307: 87.72		DNJB1_HUMAN (1-335): 7.26e-127: 368: 64.60
+	Hs
		636256 HS71L_HUMAN (2-171): 5.25e-101: 305: 84.71		DNJB1_HUMAN (1-335): 7.26e-127: 368: 64.60
+	Hs
		243275 HSP7C_HUMAN (1-171): 4.49e-104: 313: 100.00		DNJA2_HUMAN (2-336): 8.37e-120: 353: 31.46
+	Hs
		503527 HSP7C_HUMAN (1-171): 4.49e-104: 313: 100.00		DNJA1_HUMAN (5-335): 9.73e-119: 349: 32.17
+	Hs
		243312 HS71L_HUMAN (2-171): 5.25e-101: 305: 84.71		DNJA2_HUMAN (2-336): 8.37e-120: 353: 31.46
+	Hs
		92695 E9PQQ4_HUMAN (1-171): 1.1e-108: 308: 100.00		DNJA1_HUMAN (5-335): 9.73e-119: 349: 32.17
+	Hs
		483775 HS71B_HUMAN (1-171): 5.2e-102: 307: 87.72		DNJA1_HUMAN (5-335): 9.73e-119: 349: 32.17
+	Hs
		681341 HS71L_HUMAN (2-171): 5.25e-101: 305: 84.71		DNJA1_HUMAN (5-335): 9.73e-119: 349: 32.17
+	Dm
		505056 HSP7D_DROME (1-171): 2.61e-102: 308: 88.30		DNAJ1_DROME (1-335): 6.88e-117: 342: 54.87
+	Ce
		450534 HSP1_CAEEL (1-171): 1.59e-101: 306: 85.47		Q20774_CAEEL (1-330): 1.64e-115: 339: 52.87
+	Hs
		504897 HSP7C_HUMAN (1-171): 4.49e-104: 313: 100.00		DJB11_HUMAN (2-334): 6.07e-99: 298: 31.34
+	Hs
		714087 HS71L_HUMAN (2-171): 5.25e-101: 305: 84.71		DJB11_HUMAN (2-334): 6.07e-99: 298: 31.34
+	Hs
		504474 HSP7C_HUMAN (1-171): 4.49e-104: 313: 100.00		DNJB3_HUMAN (4-108): 5.57e-28: 108: 55.56