HitPredict

Interactor 1: SUMO1 (P63165)
Small ubiquitin-related modifier 1 (SUMO-1) (GAP-modifying protein 1) (GMP1) (SMT3 homolog 3) (Sentrin) (Ubiquitin-homology domain protein PIC1) (Ubiquitin-like protein SMT3C) (Smt3C) (Ubiquitin-like protein UBL1)
Gene: SUMO1

Interactor 2: BRD3 (Q15059)
Bromodomain-containing protein 3 (RING3-like protein)
Gene: BRD3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 101 Hs			1 726
+	Hs
		902596 SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36		BRD3_HUMAN (1-702): 7.67e-145: 442: 100.00
+	Hs
		902807 SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36		ZMYD8_HUMAN (3-725): 8.92e-52: 196: 12.21
+	Hs
		902548 SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	Hs
		879108 SUMO3_HUMAN (1-97): 1.65e-37: 123: 47.42		EP300_HUMAN (4-177): 1.2e-34: 144: 22.86
+	At
		1227573 Q8LCF9_ARATH (2-95): 5.94e-24: 92.1: 26.60		GTE2_ARATH (19-330): 5.74e-35: 142: 20.00
+	Hs
		244255 SUMO1_HUMAN (1-101): 1.01e-41: 134: 100.00		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		244207 SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		244184 SUMO3_HUMAN (1-97): 1.65e-37: 123: 47.42		BRD4_HUMAN (273-605): 9.08e-20: 96.8: 17.56
+	Hs
		902654 SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36		PB1_HUMAN (152-650): 1.14e-18: 93.3: 11.68
+	Hs
		600116 SUMO2_HUMAN (1-97): 1.77e-38: 125: 45.36		TAF1_HUMAN (23-303): 3.47e-17: 88.7: 13.52