Protein: AP2A2
AP-2 complex subunit alpha-2 (100 kDa coated vesicle protein C) (Adaptor protein complex AP-2 subunit alpha-2) (Adaptor-related protein complex 2 subunit alpha-2) (Alpha-adaptin C) (Alpha2-adaptin) (Clathrin assembly protein complex 2 alpha-C large chain) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit)

Gene: AP2A2
Organism: Mus musculus
Interactions: 30
UniProt ID: P17427

Gene Ontology (top 5):
GO:0006886 - intracellular protein transport
GO:0008289 - lipid binding
GO:0009898 - cytoplasmic side of plasma membrane
GO:0016192 - vesicle-mediated transport
GO:0019900 - kinase binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

604473

EPS15
Epidermal growth factor receptor substrate 15

2

20

Small-scale

0.629

High

604478

AP2S1
AP-2 complex subunit sigma

1

20

High-throughput

0.618

High

604493

NECP1
Adaptin ear-binding coat-associated protein 1

1

12

Small-scale

0.618

High

604485

NEB2
Neurabin-2

2

9

High-throughput

0.584

High

604481

AGAP2
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2

1

6

High-throughput

0.536

High

604484

FXR1
RNA-binding protein FXR1

1

6

High-throughput

0.536

High

604479

TNIK
Traf2 and NCK-interacting protein kinase

1

4

High-throughput

0.489

High

604489

PEX5R
PEX5-related protein

1

3

High-throughput

0.489

High

97354

PRRT2
Proline-rich transmembrane protein 2

1

8

High-throughput

0.479

High

108442

G3X9H5
Huntingtin

1

7

High-throughput

0.479

High

542825

RARA
Retinoic acid receptor alpha

1

14

Small-scale

0.479

High

604472

DYN1
Dynamin-1

1

9

Small-scale

0.479

High

604477

ATX1
Ataxin-1

1

7

High-throughput

0.479

High

604483

AP180
Clathrin coat assembly protein AP180

1

13

Small-scale

0.479

High

604486

AMPH
Amphiphysin

1

20

Small-scale

0.479

High

604487

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

7

High-throughput

0.479

High

604492

ATG5
Autophagy protein 5

1

5

Small-scale

0.479

High

236553

ITB3
Integrin beta-3

1

1

High-throughput

0.457

High

508953

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

17

High-throughput

0.457

High

604474

VATA
V-type proton ATPase catalytic subunit A

1

3

High-throughput

0.445

High

97560

E9PV60
WD repeat and FYVE domain containing 4

1

8

High-throughput

0.437

High

604476

TIA1
Cytotoxic granule associated RNA binding protein TIA1

1

4

High-throughput

0.437

High

604480

MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog

1

4

Small-scale

0.437

High

604482

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

4

High-throughput

0.437

High

604491

EED
Polycomb protein EED

1

13

High-throughput

0.437

High

604494

FZR1
Fizzy-related protein homolog

1

9

High-throughput

0.437

High

551376

A4
Amyloid-beta precursor protein

1

4

Small-scale

0.408

High

604475

CAV3
Caveolin-3

1

2

High-throughput

0.407

High

604488

ANS1B
Ankyrin repeat and sterile alpha motif domain-containing protein 1B

1

8

High-throughput

0.407

High

604490

ATAT
Alpha-tubulin N-acetyltransferase 1

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025