HitPredict

Interactor 1: ACTG (P63260)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: Actg1

Interactor 2: KAT5 (Q8CHK4)
Histone acetyltransferase KAT5 (EC 2.3.1.48) (60 kDa Tat-interactive protein) (Tip60) (Histone acetyltransferase HTATIP) (Lysine acetyltransferase 5) (Protein 2-hydroxyisobutyryltransferase KAT5) (EC 2.3.1.-) (Protein acetyltransferase KAT5) (EC 2.3.1.-) (Protein crotonyltransferase KAT5) (EC 2.3.1.-)
Gene: KAT5

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	24302573, 20946988
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0035267 - NuA4 histone acetyltransferase complex
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 375 Mm			1 513
+	Hs
		891950 ACTB_HUMAN (1-375): 0: 604: 98.93		KAT5_HUMAN (1-513): 0: 841: 99.81
+	Mm
		892199 ACTB_MOUSE (1-375): 0: 604: 98.93		KAT5_MOUSE (1-513): 0: 841: 100.00
+	Hs
		929960 ACTG_HUMAN (1-375): 0: 604: 100.00		KAT5_HUMAN (1-513): 0: 841: 99.81
+	Hs
		933031 ACTS_HUMAN (2-375): 0: 594: 93.85		KAT5_HUMAN (1-513): 0: 841: 99.81
+	Mm
		933091 ACTS_MOUSE (2-375): 0: 594: 93.85		KAT5_MOUSE (1-513): 0: 841: 100.00
+	Hs
		930091 ACTH_HUMAN (2-375): 0: 592: 94.39		KAT5_HUMAN (1-513): 0: 841: 99.81
+	Mm
		930100 ACTH_MOUSE (2-375): 0: 592: 94.39		KAT5_MOUSE (1-513): 0: 841: 100.00
+	Sp
		293414 ACT_SCHPO (1-375): 0: 594: 91.47		ESA1_SCHPO (22-504): 0: 571: 40.83
+	Hs
		929955 ACTG_HUMAN (1-375): 0: 604: 100.00		KAT6A_HUMAN (70-504): 1.83e-137: 439: 37.23
+	Sc
		887703 ACT_YEAST (1-375): 0: 592: 89.07		ESA1_YEAST (21-103): 9.52e-11: 65.9: 38.10