HitPredict

Interactor 1: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Interactor 2: INF2 (Q27J81)
Inverted formin-2 (HBEBP2-binding protein C)
Gene: INF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~FH2, Actin~WH2
Common GO terms	GO:0005884 - actin filament
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 1249
+	Hs
		891803 ACTB_HUMAN (1-375): 0: 604: 98.93		INF2_HUMAN (1-1249): 0: 873: 100.00
+	Hs
		932188 ACTC_HUMAN (2-375): 0: 595: 94.39		INF2_HUMAN (1-1249): 0: 873: 100.00
+	Hs
		892064 ACTB_HUMAN (1-375): 0: 604: 98.93		DIAP3_HUMAN (10-1092): 0: 666: 21.22
+	Hs
		929974 ACTG_HUMAN (1-375): 0: 604: 100.00		FMNL2_HUMAN (10-1000): 6.58e-174: 545: 19.01
+	Hs
		892145 ACTB_HUMAN (1-375): 0: 604: 98.93		FHOD1_HUMAN (8-1069): 2.59e-160: 511: 14.30
+	Hs
		930071 ACTG_HUMAN (1-375): 0: 604: 100.00		FHOD1_HUMAN (8-1069): 2.59e-160: 511: 14.30
+	Sc
		773864 ACT_YEAST (1-375): 0: 592: 89.07		BNR1_YEAST (34-1000): 1.59e-113: 388: 15.32
+	Hs
		892135 ACTB_HUMAN (1-375): 0: 604: 98.93		DAAM1_HUMAN (507-1016): 1.8e-110: 374: 23.54
+	Hs
		1122441 ACTBL_HUMAN (2-375): 0: 734: 91.44		FMNL3_HUMAN (43-382): 2.09e-59: 224: 20.68
+	Hs
		237575 ACTB_HUMAN (1-375): 0: 604: 98.93		DIAP1_HUMAN (10-532): 2.88e-73: 269: 21.30
+	Hs
		237587 ACTC_HUMAN (2-375): 0: 595: 94.39		DIAP1_HUMAN (10-532): 2.88e-73: 269: 21.30
+	Hs
		915429 ACTA_HUMAN (2-375): 0: 594: 94.39		FMNL3_HUMAN (43-382): 2.09e-59: 224: 20.68
+	Sc
		784637 ACT_YEAST (1-375): 0: 592: 89.07		BNI1_YEAST (19-298): 8.22e-30: 131: 12.17
+	Sp
		501585 ACT_SCHPO (1-375): 0: 594: 91.47		CDC12_SCHPO (1-270): 1.07e-20: 101: 15.96
+	Hs
		892076 ACTB_HUMAN (1-375): 0: 604: 98.93		FMN2_HUMAN (495-827): 8.34e-11: 68.9: 25.71
+	Hs
		930029 ACTG_HUMAN (1-375): 0: 604: 100.00		FMN2_HUMAN (495-827): 8.34e-11: 68.9: 25.71
+	Hs
		932414 ACTC_HUMAN (2-375): 0: 595: 94.39		FMN2_HUMAN (495-827): 8.34e-11: 68.9: 25.71