HitPredict

Interactor 1: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Interactor 2: MRTFB (Q9ULH7)
Myocardin-related transcription factor B (MRTF-B) (MKL/myocardin-like protein 2) (Megakaryoblastic leukemia 2)
Gene: MRTFB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~RPEL
Common GO terms	GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 1088
+	Hs
		892105 ACTB_HUMAN (1-375): 0: 604: 98.93		MRTFB_HUMAN (1-1088): 4.21e-107: 362: 100.00
+	Hs
		932446 ACTC_HUMAN (2-375): 0: 595: 94.39		MRTFB_HUMAN (1-1088): 4.21e-107: 362: 100.00
+	Hs
		554315 ACTBL_HUMAN (2-375): 0: 734: 91.44		MUC1_HUMAN (152-1077): 1.05e-51: 200: 11.70
+	Hs
		1122431 ACTBL_HUMAN (2-375): 0: 734: 91.44		SRCAP_HUMAN (397-1085): 3.34e-17: 89.8: 9.96
+	Hs
		965115 ACTBL_HUMAN (2-375): 0: 734: 91.44		ANK2_HUMAN (116-962): 1.33e-15: 84.5: 12.47
+	Hs
		554290 ACTA_HUMAN (2-375): 0: 594: 94.39		MUC1_HUMAN (152-1077): 1.05e-51: 200: 11.70
+	Hs
		932156 ACTC_HUMAN (2-375): 0: 595: 94.39		MDC1_HUMAN (1-1028): 4.3e-33: 141: 8.82
+	Hs
		891853 ACTB_HUMAN (1-375): 0: 604: 98.93		SRCAP_HUMAN (397-1085): 3.34e-17: 89.8: 9.96
+	Hs
		929905 ACTG_HUMAN (1-375): 0: 604: 100.00		SRCAP_HUMAN (397-1085): 3.34e-17: 89.8: 9.96
+	Hs
		891956 ACTB_HUMAN (1-375): 0: 604: 98.93		MRTFA_HUMAN (207-1088): 3.88e-16: 85.9: 13.75
+	Hs
		929962 ACTG_HUMAN (1-375): 0: 604: 100.00		MRTFA_HUMAN (207-1088): 3.88e-16: 85.9: 13.75
+	Hs
		891699 ACTB_HUMAN (1-375): 0: 604: 98.93		ANK2_HUMAN (116-962): 1.33e-15: 84.5: 12.47
+	Hs
		932219 ACTC_HUMAN (2-375): 0: 595: 94.39		SRCAP_HUMAN (397-1085): 3.34e-17: 89.8: 9.96
+	Dm
		501445 ACT5_DROME (2-375): 0: 598: 95.46		CPN_DROME (486-1086): 3.68e-16: 85.8: 10.11
+	Hs
		932312 ACTC_HUMAN (2-375): 0: 595: 94.39		MRTFA_HUMAN (207-1088): 3.88e-16: 85.9: 13.75
+	Hs
		930079 ACTH_HUMAN (2-375): 0: 592: 94.39		ANK2_HUMAN (116-962): 1.33e-15: 84.5: 12.47
+	Hs
		891768 ACTB_HUMAN (1-375): 0: 604: 98.93		NCOA6_HUMAN (110-1067): 3.09e-09: 63.6: 8.12
+	Hs
		203220 ACTC_HUMAN (2-375): 0: 595: 94.39		SYNJ1_HUMAN (260-700): 1.17e-11: 71.6: 9.73