HitPredict

Interactor 1: ACTH (P63267)
Actin, gamma-enteric smooth muscle (EC 3.6.4.-) (Alpha-actin-3) (Gamma-2-actin) (Smooth muscle gamma-actin) [Cleaved into: Actin, gamma-enteric smooth muscle, intermediate form]
Gene: ACTG2

Interactor 2: ALPK2 (Q86TB3)
Alpha-protein kinase 2 (EC 2.7.11.1) (Heart alpha-protein kinase)
Gene: ALPK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~I-set
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 376 Hs			1 2170
+	Mm
		1206349 ACTBL_MOUSE (1-376): 0: 721: 88.83		TRPM7_MOUSE (1821-2167): 1.48e-111: 398: 19.89
+	Mm
		892207 ACTB_MOUSE (1-376): 0: 601: 93.35		TRPM7_MOUSE (1821-2167): 1.48e-111: 398: 19.89
+	Hs
		255843 ACTBL_HUMAN (1-376): 0: 713: 87.77		OBSL1_HUMAN (5-105): 4.13e-10: 67.5: 22.86
+	Hs
		891928 ACTB_HUMAN (1-376): 0: 601: 93.35		PALLD_HUMAN (4-104): 1.31e-20: 102: 27.72
+	Hs
		891771 ACTB_HUMAN (1-376): 0: 601: 93.35		MYPC3_HUMAN (2-186): 5.02e-14: 80.3: 15.87
+	Hs
		932159 ACTC_HUMAN (2-376): 0: 598: 98.67		MYPC3_HUMAN (2-186): 5.02e-14: 80.3: 15.87
+	Hs
		255668 ACTC_HUMAN (2-376): 0: 598: 98.67		OBSL1_HUMAN (5-105): 4.13e-10: 67.5: 22.86
+	Hs
		255670 ACTS_HUMAN (2-376): 0: 598: 98.13		OBSL1_HUMAN (5-105): 4.13e-10: 67.5: 22.86