HitPredict

Interactor 1: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Interactor 2: NCOR2 (Q9Y618)
Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)
Gene: NCOR2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	20555024
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 158 Hs			1 2514
+	Hs
		261465 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Mm
		930493 UBC9_MOUSE (1-158): 1.43e-70: 211: 100.00		Q8BK32_MOUSE (1-280): 1.47e-40: 155: 49.66
+	Hs
		1297360 UB2E2_HUMAN (3-156): 7.29e-69: 208: 33.77		MINT_HUMAN (80-1321): 6.8e-20: 100: 8.11
+	Hs
		930320 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		TITIN_HUMAN (1125-2056): 5.55e-11: 70.9: 8.61
+	Hs
		829039 UBE2A_HUMAN (1-154): 3.37e-67: 202: 41.56		TITIN_HUMAN (1125-2056): 5.55e-11: 70.9: 8.61