HitPredict

Interactor 1: UBC9 (P63280)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (mUBC9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I)
Gene: Ube2i

Interactor 2: IKZF1 (Q03267)
DNA-binding protein Ikaros (Ikaros family zinc finger protein 1) (Lymphoid transcription factor LyF-1)
Gene: IKZF1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	15767674
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 158 Mm			1 517
+	Mm
		140044 UBC9_MOUSE (1-158): 1.43e-70: 211: 100.00		IKZF3_MOUSE (13-516): 6.99e-159: 463: 53.00
+	Hs
		930448 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		IKZF3_HUMAN (3-516): 8.3e-155: 453: 50.86
+	Hs
		1033668 Q7KZS0_HUMAN (1-137): 2.27e-71: 214: 100.00		IKZF1_HUMAN (1-517): 1.99e-142: 421: 90.42
+	Hs
		930194 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		IKZF1_HUMAN (1-517): 1.99e-142: 421: 90.42
+	Hs
		930394 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		IKZF5_HUMAN (62-515): 1.58e-96: 300: 22.55
+	Hs
		930306 UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00		ZN420_HUMAN (436-517): 5.03e-19: 92.5: 20.73
+	Dm
		592800 Q7KNM2_DROME (1-158): 1.41e-66: 201: 85.44		CF2_DROME (118-218): 3.07e-18: 89.4: 40.37