HitPredict

Interactor 1: HSP72 (P54652)
Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2) (Heat shock protein family A member 2)
Gene: HSPA2

Interactor 2: Q53FC7 (Q53FC7)
Heat shock 70 kDa protein 6
Gene: Q53FC7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HSP70~HSP70
Common GO terms	GO:0005524 - ATP binding GO:0140662 - ATP-dependent protein folding chaperone
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 639 Hs			1 643
+	Hs
		600780 HSP72_HUMAN (1-639): 0: 954: 100.00		HSP76_HUMAN (1-643): 0: 986: 99.22
+	Hs
		600750 HS71L_HUMAN (2-639): 0: 952: 81.90		HSP76_HUMAN (1-643): 0: 986: 99.22
+	Hs
		536447 HSP7C_HUMAN (3-616): 0: 946: 87.95		HSP76_HUMAN (1-643): 0: 986: 99.22
+	Hs
		600725 HSP76_HUMAN (2-639): 0: 945: 77.45		HSP76_HUMAN (1-643): 0: 986: 99.22
+	Hs
		761355 HSP72_HUMAN (1-639): 0: 954: 100.00		HS71L_HUMAN (1-643): 0: 976: 78.85
+	Hs
		536824 HSP72_HUMAN (1-639): 0: 954: 100.00		HSP7C_HUMAN (4-615): 0: 953: 78.76
+	Hs
		536609 HS71L_HUMAN (2-639): 0: 952: 81.90		HSP7C_HUMAN (4-615): 0: 953: 78.76
+	Mm
		609022 HS71B_MOUSE (3-639): 0: 942: 82.58		HS71A_MOUSE (5-643): 0: 958: 81.22
+	Hs
		536371 HSP7C_HUMAN (3-616): 0: 946: 87.95		HSP7C_HUMAN (4-615): 0: 953: 78.76
+	Mm
		989233 HSP7C_MOUSE (3-616): 0: 945: 87.79		HSP7C_MOUSE (4-615): 0: 953: 78.76
+	Hs
		930833 HSP72_HUMAN (1-639): 0: 954: 100.00		HSP72_HUMAN (3-643): 0: 940: 77.14
+	Mm
		602281 HSP72_MOUSE (1-639): 0: 946: 97.97		HSP72_MOUSE (3-614): 0: 935: 78.99
+	Sc
		481439 HSP73_YEAST (7-639): 0: 914: 72.22		HSP73_YEAST (8-643): 0: 928: 70.43