Interactor 1: C5AR1 (P21730)
C5a anaphylatoxin chemotactic receptor 1 (C5a anaphylatoxin chemotactic receptor) (C5a-R) (C5aR) (CD antigen CD88)
Gene: C5AR1
Interactor 2: ARRB1 (P49407)
Beta-arrestin-1 (Arrestin beta-1) (Non-visual arrestin-2)
Gene: ARRB1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12464600 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | 7tm_1~Arrestin_C, 7tm_1~Arrestin_N |
| Common GO terms | GO:0005886 - plasma membrane GO:0007165 - signal transduction GO:0070374 - positive regulation of ERK1 and ERK2 cascade |
| Homologous interactions | 13 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
