Interactor 1: D3ZVH5 (D3ZVH5)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27)
Gene: Mdm2
Interactor 2: HIF1A (O35800)
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha)
Gene: HIF1A
Species: Rattus norvegicus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.60 | 0.479 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19950214 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0001568 - blood vessel development GO:0002039 - p53 binding GO:0005634 - nucleus GO:0005737 - cytoplasm and 15 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
