HitPredict

Interactor 1: EPHB4 (P54760)
Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)
Gene: EPHB4

Interactor 2: PCDG5 (Q9Y5G8)
Protocadherin gamma-A5 (PCDH-gamma-A5)
Gene: PCDHGA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007155 - cell adhesion
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 987 Hs			1 931
+	Hs
		932019 EPHB4_HUMAN (1-987): 0: 1120: 100.00		PCDG6_HUMAN (1-916): 0: 1100: 76.23
+	Hs
		932018 EPHB4_HUMAN (1-987): 0: 1120: 100.00		PCDG7_HUMAN (1-916): 0: 1093: 75.35
+	Hs
		932022 EPHB4_HUMAN (1-987): 0: 1120: 100.00		PCDC2_HUMAN (25-904): 0: 990: 39.44
+	Hs
		932021 EPHB4_HUMAN (1-987): 0: 1120: 100.00		PCDA8_HUMAN (24-904): 0: 965: 39.55
+	Hs
		640341 EPHA1_HUMAN (11-969): 0: 946: 39.96		PCDA8_HUMAN (24-904): 0: 965: 39.55
+	Hs
		932017 EPHB4_HUMAN (1-987): 0: 1120: 100.00		PCDB3_HUMAN (12-773): 0: 615: 47.26
+	Hs
		932011 EPHB4_HUMAN (1-987): 0: 1120: 100.00		PCDAC_HUMAN (2-372): 3.81e-59: 220: 23.96
+	Hs
		720375 UFO_HUMAN (265-915): 9.19e-150: 468: 24.51		PCDB3_HUMAN (12-773): 0: 615: 47.26