HitPredict

Interactor 1: TPM4 (P67936)
Tropomyosin alpha-4 chain (TM30p1) (Tropomyosin-4)
Gene: TPM4

Interactor 2: PIM3 (Q86V86)
Serine/threonine-protein kinase pim-3 (EC 2.7.11.1)
Gene: PIM3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 326
+	Hs
		451277 TPM1_HUMAN (4-248): 1.43e-48: 163: 68.16		PIM3_HUMAN (1-326): 5.96e-126: 365: 100.00
+	Hs
		451333 TPM1_HUMAN (4-248): 1.43e-48: 163: 68.16		AKT3_HUMAN (27-323): 2.57e-123: 363: 23.00
+	Hs
		418995 TPM3_HUMAN (4-248): 6.47e-47: 159: 69.39		PIM3_HUMAN (1-326): 5.96e-126: 365: 100.00
+	Hs
		681779 TPM4_HUMAN (1-248): 5.49e-47: 158: 100.00		AKT1_HUMAN (11-323): 2.69e-123: 363: 23.03
+	Hs
		932075 TPM4_HUMAN (1-248): 5.49e-47: 158: 100.00		AKT3_HUMAN (27-323): 2.57e-123: 363: 23.00
+	Hs
		99847 F5H7S3_HUMAN (1-244): 1.92e-46: 156: 75.41		AKT3_HUMAN (27-323): 2.57e-123: 363: 23.00
+	Hs
		434350 TPM2_HUMAN (4-248): 5.04e-42: 146: 69.39		AKT2_HUMAN (11-323): 4.07e-126: 371: 23.71
+	Hs
		434403 TPM2_HUMAN (4-248): 5.04e-42: 146: 69.39		PIM3_HUMAN (1-326): 5.96e-126: 365: 100.00
+	Hs
		434349 TPM2_HUMAN (4-248): 5.04e-42: 146: 69.39		AKT1_HUMAN (11-323): 2.69e-123: 363: 23.03
+	Hs
		111618 K7ENT6_HUMAN (36-248): 4.17e-39: 137: 96.24		AKT3_HUMAN (27-323): 2.57e-123: 363: 23.00
+	Hs
		434431 TPM2_HUMAN (4-248): 5.04e-42: 146: 69.39		SIK2_HUMAN (40-294): 8.16e-34: 133: 32.82