HitPredict

Interactor 1: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Interactor 2: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30890647
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 2115
+	Hs
		892003 ACTB_HUMAN (4-377): 0: 599: 94.12		CP250_HUMAN (1-1659): 6.01e-59: 228: 13.08
+	Mm
		892205 ACTB_MOUSE (4-377): 0: 599: 94.12		MYH9_MOUSE (1089-2070): 6.61e-40: 165: 12.96
+	Rn
		892228 ACTB_RAT (4-377): 0: 599: 94.12		MYH9_RAT (1-858): 1.6e-39: 164: 12.81
+	Hs
		724738 ACTB_HUMAN (4-377): 0: 599: 94.12		MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62
+	Hs
		724762 ACTG_HUMAN (4-377): 0: 599: 94.39		MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62
+	Hs
		724766 ACTC_HUMAN (1-377): 0: 599: 100.00		MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62
+	Hs
		724767 ACTS_HUMAN (1-377): 0: 599: 98.94		MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62
+	Hs
		725136 ACTC_HUMAN (1-377): 0: 599: 100.00		MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34
+	Mm
		930101 ACTH_MOUSE (4-377): 0: 591: 98.93		PLEC_MOUSE (21-1207): 2.95e-35: 150: 12.47
+	Rn
		892236 ACTB_RAT (4-377): 0: 599: 94.12		MYH10_RAT (1281-2075): 2.06e-32: 140: 12.22
+	Hs
		929869 ACTG_HUMAN (4-377): 0: 599: 94.39		PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37
+	Hs
		932171 ACTC_HUMAN (1-377): 0: 599: 100.00		PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37
+	Hs
		725135 ACTH_HUMAN (4-377): 0: 591: 98.93		MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34
+	Dm
		361160 ACT4_DROME (1-377): 0: 649: 92.57		MYSA_DROME (478-1618): 3.93e-09: 64.3: 19.72
+	Hs
		932157 ACTC_HUMAN (1-377): 0: 599: 100.00		GOGB1_HUMAN (1105-2077): 1.12e-19: 99.3: 9.49
+	Hs
		518849 ACTC_HUMAN (1-377): 0: 599: 100.00		TPR_HUMAN (2-620): 2.42e-18: 94.7: 12.04
+	Hs
		828573 ACTC_HUMAN (1-377): 0: 599: 100.00		CENPF_HUMAN (1458-2037): 1.6e-10: 69.3: 9.97
+	Dm
		404232 ACT6_DROME (1-377): 0: 594: 92.84		MYSA_DROME (478-1618): 3.93e-09: 64.3: 19.72