HitPredict

Interactor 1: ACTC (P68032)
Actin, alpha cardiac muscle 1 (EC 3.6.4.-) (Alpha-cardiac actin) [Cleaved into: Actin, alpha cardiac muscle 1, intermediate form]
Gene: ACTC1

Interactor 2: ASPM (Q8IZT6)
Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog)
Gene: ASPM

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30890647
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~CH
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 377 Hs			1 3477
+	Hs
		506816 ACTB_HUMAN (4-377): 0: 599: 94.12		SPTB1_HUMAN (929-2995): 1.76e-100: 365: 9.24
+	Dm
		361167 ACT4_DROME (1-377): 0: 649: 92.57		ACTN_DROME (936-1799): 6.36e-87: 309: 12.79
+	Ce
		184696 ACT4_CAEEL (1-377): 0: 601: 94.43		O17666_CAEEL (626-1138): 5.29e-92: 330: 19.17
+	Hs
		929869 ACTG_HUMAN (4-377): 0: 599: 94.39		PLEC_HUMAN (1241-2615): 6.18e-30: 134: 10.29
+	Hs
		932171 ACTC_HUMAN (1-377): 0: 599: 100.00		PLEC_HUMAN (1241-2615): 6.18e-30: 134: 10.29
+	Hs
		513848 ACTS_HUMAN (1-377): 0: 599: 98.94		DMD_HUMAN (1507-3476): 2.32e-27: 125: 7.73
+	Sp
		293470 ACT_SCHPO (4-377): 0: 645: 89.04		MYO52_SCHPO (1259-1595): 8.37e-09: 64.1: 15.34
+	Hs
		930015 ACTG_HUMAN (4-377): 0: 599: 94.39		MYO5C_HUMAN (2658-3307): 6.45e-23: 110: 10.82
+	Hs
		932396 ACTC_HUMAN (1-377): 0: 599: 100.00		MYO5C_HUMAN (2658-3307): 6.45e-23: 110: 10.82
+	Dm
		51919 ACT3_DROME (1-377): 0: 595: 92.57		A1Z6Z9_DROME (1331-1972): 6.12e-20: 100: 12.17
+	Hs
		214544 ACTB_HUMAN (4-377): 0: 599: 94.12		MYO1B_HUMAN (1752-2123): 7.21e-15: 83.8: 16.24
+	Hs
		214550 ACTC_HUMAN (1-377): 0: 599: 100.00		MYO1B_HUMAN (1752-2123): 7.21e-15: 83.8: 16.24
+	Dm
		284844 ACT1_DROME (1-377): 0: 598: 94.43		O77291_DROME (1656-3474): 1.94e-12: 76.3: 7.53
+	Hs
		164588 ACTB_HUMAN (4-377): 0: 599: 94.12		SPTN2_HUMAN (1892-3473): 1.5e-11: 73.3: 8.86
+	Hs
		891697 ACTB_HUMAN (4-377): 0: 599: 94.12		SPTB2_HUMAN (2326-3469): 1.32e-10: 70.2: 8.55
+	Hs
		929824 ACTG_HUMAN (4-377): 0: 599: 94.39		SPTB2_HUMAN (2326-3469): 1.32e-10: 70.2: 8.55
+	Hs
		932107 ACTC_HUMAN (1-377): 0: 599: 100.00		SPTB2_HUMAN (2326-3469): 1.32e-10: 70.2: 8.55
+	Hs
		112131 ACTG_HUMAN (4-377): 0: 599: 94.39		M0R0P8_HUMAN (1279-1443): 5.11e-09: 64.8: 25.30
+	Hs
		891744 ACTB_HUMAN (4-377): 0: 599: 94.12		MYO9B_HUMAN (1279-1443): 4.98e-09: 64.8: 25.30
+	Hs
		929850 ACTG_HUMAN (4-377): 0: 599: 94.39		MYO9B_HUMAN (1279-1443): 4.98e-09: 64.8: 25.30